Detalles de la búsqueda
1.
A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy.
J Biomol NMR
; 75(4-5): 167-178, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33856612
2.
Allosteric Inhibition of the SARS-CoV-2 Main Protease: Insights from Mass Spectrometry Based Assays*.
Angew Chem Int Ed Engl
; 59(52): 23544-23548, 2020 12 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32841477
3.
The complex of Plasmodium falciparum falcipain-2 protease with an (E)-chalcone-based inhibitor highlights a novel, small, molecule-binding site.
Malar J
; 18(1): 388, 2019 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31791339
4.
Probing the ß-pocket of the active site of human liver glycogen phosphorylase with 3-(C-ß-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg Chem
; 77: 485-493, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29454281
5.
van der Waals interactions govern C-ß-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J Struct Biol
; 199(1): 57-67, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28483603
6.
Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.
Bioorg Chem
; 63: 152-65, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26551065
7.
Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants.
Molecules
; 20(6): 10848-65, 2015 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-26076107
8.
Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-ß-d-glucopyranosylamines.
Bioorg Med Chem
; 22(17): 4810-25, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25092521
9.
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
iScience
; 26(10): 107919, 2023 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37822503
10.
Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg Med Chem
; 20(24): 7184-93, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23122937
11.
Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure
; 30(5): 671-684.e5, 2022 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35240058
12.
Structures of the Plasmodium falciparum heat-shock protein 70-x ATPase domain in complex with chemical fragments identify conserved and unique binding sites.
Acta Crystallogr F Struct Biol Commun
; 77(Pt 8): 262-268, 2021 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34341192
13.
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Curr Drug Discov Technol
; 15(1): 41-53, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-28625148
14.
Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes.
Curr Med Chem
; 24(4): 384-403, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-27855623
15.
Nanomolar Inhibitors of Glycogen Phosphorylase Based on ß-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J Med Chem
; 60(22): 9251-9262, 2017 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28925695
16.
The ammonium sulfate inhibition of human angiogenin.
FEBS Lett
; 590(17): 3005-18, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27483019
17.
Synthetic, enzyme kinetic, and protein crystallographic studies of C-ß-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Eur J Med Chem
; 123: 737-745, 2016 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27522507
18.
Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b.
FEBS Lett
; 589(15): 1787-94, 2015 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-25980608
19.
Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(ß-D-glucopyranosyl) urea inhibitors.
Curr Top Med Chem
; 15(23): 2373-89, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26088352
20.
Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase.
Food Chem Toxicol
; 67: 35-43, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24556570