Detalles de la búsqueda
1.
Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.
Bioorg Med Chem
; 23(13): 3638-54, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25936262
2.
Retinoic acid signaling pathways in development and diseases.
Bioorg Med Chem
; 22(2): 673-83, 2014 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24393720
3.
Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors.
Bioorg Chem
; 51: 24-30, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24095934
4.
2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
Bioorg Chem
; 40(1): 67-78, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22000119
5.
2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study.
Bioorg Med Chem Lett
; 20(1): 42-7, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19954977
6.
2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
Bioorg Med Chem
; 18(1): 377-86, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19939682
7.
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines.
Bioorg Med Chem
; 18(9): 3066-77, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20392646
8.
Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
Bioorg Med Chem
; 18(6): 2245-2254, 2010 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20188578
9.
Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities.
Eur J Med Chem
; 43(4): 675-82, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17673337
10.
Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells.
ACS Omega
; 2(10): 6349-6360, 2017 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-29104951
11.
A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
Eur J Med Chem
; 113: 228-45, 2016 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26945111
12.
Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.
Eur J Med Chem
; 90: 360-78, 2015 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-25437622
13.
A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases.
J Med Chem
; 58(3): 1100-22, 2015 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25603122
14.
Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
Eur J Med Chem
; 84: 555-65, 2014 Sep 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25062006
15.
Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor.
Eur J Med Chem
; 80: 428-38, 2014 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24796883
16.
Use of zebrafish in chemical biology and drug discovery.
Future Med Chem
; 5(17): 2103-16, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24215349
17.
Boron chemicals in diagnosis and therapeutics.
Future Med Chem
; 5(6): 653-76, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23617429
18.
Dihydroxylated 2,4,6-triphenyl pyridines: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
Eur J Med Chem
; 49: 219-28, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22318164
19.
Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety.
Eur J Med Chem
; 52: 123-36, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22503656
20.
Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
Eur J Med Chem
; 46(8): 3201-9, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21601964