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1.
Discovery of N-(6-(5-fluoro-2-(piperidin-1-yl)phenyl)pyridazin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)methanesulfonamide as a brain-permeable and metabolically stable kynurenine monooxygenase inhibitor.
Bioorg Med Chem Lett
; 44: 128115, 2021 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34015507
2.
N-(6-phenylpyridazin-3-yl)benzenesulfonamides as highly potent, brain-permeable, and orally active kynurenine monooxygenase inhibitors.
Bioorg Med Chem Lett
; 33: 127753, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33359168
3.
Synthesis, structure-activity relationships and biological evaluation of 4,5,6,7-tetrahydropyrazolopyrazines as metabotropic glutamate receptor 5 negative allosteric modulators.
Bioorg Med Chem Lett
; 26(16): 3866-9, 2016 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27432763
4.
The Impact of Intestinal Microbiota and Toll-like Receptor 2 Signaling on α-Synuclein Pathology in Nontransgenic Mice Injected with α-Synuclein Preformed Fibrils.
Microorganisms
; 12(1)2024 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38257933
5.
DSR-98776, a novel selective mGlu5 receptor negative allosteric modulator with potent antidepressant and antimanic activity.
Eur J Pharmacol
; 757: 11-20, 2015 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25823809
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