Detalles de la búsqueda
1.
A novel approach to oxazole-containing diterpenoid synthesis from plant roots: salviamines E and F.
Org Biomol Chem
; 17(3): 655-663, 2019 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-30575839
2.
A novel approach to sesquiterpenoid benzoxazole synthesis from marine sponges: nakijinols A, B and E-G.
Org Biomol Chem
; 16(19): 3639-3647, 2018 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29708256
3.
Antitumor activity and pharmacologic characterization of the depsipeptide analog as a novel histone deacetylase/ phosphatidylinositol 3-kinase dual inhibitor.
Cancer Sci
; 108(7): 1469-1475, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-28406576
4.
Total Synthesis of Thailandepsin B, a Potent HDAC Inhibitor Isolated from a Microorganism.
Chem Pharm Bull (Tokyo)
; 64(7): 913-7, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27373645
5.
Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors.
Cancer Sci
; 106(2): 208-15, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25492515
6.
Clinical effect of biapenem on nursing and healthcare-associated pneumonia (NHCAP).
J Infect Chemother
; 21(8): 592-5, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26050019
7.
Enantioselective total synthesis of dysidavarone A, a novel sesquiterpenoid quinone from the marine sponge Dysidea avara.
Chemistry
; 20(9): 2436-9, 2014 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24482283
8.
Romidepsin (FK228) and its analogs directly inhibit phosphatidylinositol 3-kinase activity and potently induce apoptosis as histone deacetylase/phosphatidylinositol 3-kinase dual inhibitors.
Cancer Sci
; 103(11): 1994-2001, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22924958
9.
Trends in antimicrobial susceptibility of Streptococcus pneumoniae in the Tohoku district of Japan: a longitudinal analysis from 1998 to 2007.
Tohoku J Exp Med
; 220(1): 47-57, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20046052
10.
Enantioselective total synthesis of (-)-candelalides A, B and C: potential Kv1.3 blocking immunosuppressive agents.
Chemistry
; 15(12): 2826-45, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19191240
11.
Total synthesis of the bicyclic depsipeptide HDAC inhibitors spiruchostatins A and B, 5''-epi-spiruchostatin B, FK228 (FR901228) and preliminary evaluation of their biological activity.
Chemistry
; 15(42): 11174-86, 2009 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19760730
12.
In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells.
Cancer Med
; 8(12): 5662-5672, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31364822
13.
Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism.
Chem Commun (Camb)
; (14): 1677-9, 2008 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-18368162
14.
Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors.
Eur J Med Chem
; 121: 592-609, 2016 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27318982
15.
Low-dose spiruchostatin-B, a potent histone deacetylase inhibitor enhances radiation-induced apoptosis in human lymphoma U937 cells via modulation of redox signaling.
Free Radic Res
; 50(6): 596-610, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27108737
16.
Enantioselective total synthesis of (-)-candelalide A, a novel blocker of the voltage-gated potassium channel Kv1.3 for an immunosuppressive agent.
Org Lett
; 7(17): 3745-8, 2005 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-16092865
17.
Total synthesis and absolute configuration of otteliones A and B, novel and potent antitumor agents from a freshwater plant.
Org Lett
; 5(21): 3903-6, 2003 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-14535739
18.
A new strategy toward the total synthesis of stachyflin, a potent anti-influenza A virus agent: concise route to the tetracyclic core structure.
Org Lett
; 4(25): 4483-6, 2002 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-12465918
19.
Predicting the structures of complexes between phosphoinositide 3-kinase (PI3K) and romidepsin-related compounds for the drug design of PI3K/histone deacetylase dual inhibitors using computational docking and the ligand-based drug design approach.
J Mol Graph Model
; 54: 46-53, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25254927
20.
Total synthesis of burkholdacs A and B and 5,6,20-tri-epi-burkholdac A: HDAC inhibition and antiproliferative activity.
Eur J Med Chem
; 76: 301-13, 2014 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24589486