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1.
Novel Compound Induces Erythropoietin Secretion through Liver Effects in Chronic Kidney Disease Patients and Healthy Volunteers.
Am J Nephrol
; 48(3): 157-164, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30176654
2.
Discovery of 3-Chloro-N-{(S)-[3-(1-ethyl-1H-pyrazol-4-yl)phenyl][(2S)-piperidine-2-yl]methyl}-4-(trifluoromethyl)pyridine-2-carboxamide as a Potent Glycine Transporter 1 Inhibitor.
Chem Pharm Bull (Tokyo)
; 64(9): 1321-37, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27581637
3.
Identification of 1-Methyl-N-(propan-2-yl)-N-({2-[4-(trifluoromethoxy)phenyl]pyridin-4-yl}methyl)-1H-imidazole-4-carboxamide as a Potent and Orally Available Glycine Transporter 1 Inhibitor.
Chem Pharm Bull (Tokyo)
; 64(11): 1630-1640, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27803474
4.
[Pharmacological and clinical profile of asciminib hydrochloride, a novel first-in-class tyrosine kinase inhibitor specifically targeting ABL myristoyl pocket].
Nihon Yakurigaku Zasshi
; 158(3): 273-281, 2023.
Artículo
en Japonés
| MEDLINE | ID: mdl-37121712
5.
Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist.
Bioorg Med Chem
; 16(8): 4359-66, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18348906
6.
Efficacy of a glycine transporter 1 inhibitor TASP0315003 in animal models of cognitive dysfunction and negative symptoms of schizophrenia.
Psychopharmacology (Berl)
; 232(15): 2849-61, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25869273
7.
(1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment.
J Med Chem
; 53(8): 3247-61, 2010 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-20302302
8.
In vitro and in vivo evaluation of the metabolism and bioavailability of ester prodrugs of mgs0039 (3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid), a potent metabotropic glutamate receptor antagonist.
Drug Metab Dispos
; 34(3): 369-74, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16326817
9.
Increase of intracellular glutathione by low-dose gamma-ray irradiation is mediated by transcription factor AP-1 in RAW 264.7 cells.
Biol Pharm Bull
; 26(1): 19-23, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12520165
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