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1.
Click ferrocenyl-erlotinib conjugates active against erlotinib-resistant non-small cell lung cancer cells in vitro.
Bioorg Chem
; 119: 105514, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34864281
2.
In silico design and in vitro assessment of anti-Helicobacter pylori compounds as potential small-molecule arginase inhibitors.
Mol Divers
; 26(6): 3365-3378, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34997872
3.
Synthesis, biological evaluation and molecular docking studies of novel 1,2,3-triazole-quinazolines as antiproliferative agents displaying ERK inhibitory activity.
Bioorg Chem
; 113: 104982, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34020277
4.
The Enantiomeric Discrimination of 5-Hexyl-2-methyl-3,4-dihydro-2H-pyrrole by Sulfobutyl ether-ß-cyclodextrin: A Case Study.
Molecules
; 26(9)2021 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-33947062
5.
Synthesis and biological evaluation of 2'-Aminochalcone: A multi-target approach to find drug candidates to treat Alzheimer's disease.
Bioorg Chem
; 103: 104201, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32890999
6.
In Silico, In Vitro, and In Vivo Antitumor and Anti-Inflammatory Evaluation of a Standardized Alkaloid-Enriched Fraction Obtained from Boehmeria caudata Sw. Aerial Parts.
Molecules
; 25(17)2020 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32899132
7.
Evaluation of Lignans from Piper cubeba against Schistosoma mansoni Adult Worms: A Combined Experimental and Theoretical Study.
Chem Biodivers
; 16(1): e1800305, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30335227
8.
Identification of a novel putative inhibitor of the Plasmodium falciparum purine nucleoside phosphorylase: exploring the purine salvage pathway to design new antimalarial drugs.
Mol Divers
; 21(3): 677-695, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28523625
9.
Modulation of Pseudomonas aeruginosa quorum sensing by ajoene through direct competition with small RNAs for binding at the proximal site of Hfq - A structure-based perspective.
Gene
; 877: 147506, 2023 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37224934
10.
Entering the Sugar Rush Era: Revisiting the Antihyperglycemic Activities of Biguanides after a Century of Metformin Discovery.
Curr Med Chem
; 30(22): 2542-2561, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35996245
11.
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics.
Mini Rev Med Chem
; 22(18): 2318-2331, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35264091
12.
Search for a platelet-activating factor receptor in the Trypanosoma cruzi proteome: a potential target for Chagas disease chemotherapy.
Mem Inst Oswaldo Cruz
; 106(8): 957-67, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22241117
13.
Structural basis for the design of allosteric inhibitors of the Aurora kinase A enzyme in the cancer chemotherapy.
Biochim Biophys Acta Gen Subj
; 1864(1): 129448, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31676293
14.
Insights into the Design of Inhibitors of the Urease Enzyme - A Major Target for the Treatment of Helicobacter pylori Infections.
Curr Med Chem
; 27(23): 3967-3982, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-30827224
15.
1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives: design, synthesis and molecular assessment toward C6 glioma cell line.
Future Med Chem
; 12(8): 689-708, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32193951
16.
Psoralen and bergapten: in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo.
J Pharm Pharm Sci
; 12(3): 378-87, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-20067712
17.
Search for Potential Inducible Nitric Oxide Synthase Inhibitors with Favorable ADMET Profiles for the Therapy of Helicobacter pylori Infections.
Curr Top Med Chem
; 19(30): 2795-2804, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31721712
18.
A Highly Active Triterpene Derivative Capable |of Biofilm Damage to Control Cryptococcus spp.
Biomolecules
; 9(12)2019 12 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31817559
19.
Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans.
BMC Pharmacol Toxicol
; 20(Suppl 1): 76, 2019 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31852548
20.
Molecular dynamics, density functional, ADMET predictions, virtual screening, and molecular interaction field studies for identification and evaluation of novel potential CDK2 inhibitors in cancer therapy.
J Phys Chem A
; 112(38): 8902-10, 2008 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-18698751