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1.
Discovery of a Novel Fluoroquinolone Antibiotic Candidate WFQ-228 with Potent Antimicrobial Activity and the Potential to Overcome Major Drug Resistance.
Chem Pharm Bull (Tokyo)
; 66(3): 235-238, 2018 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29321384
2.
Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption.
J Nutr
; 146(2): 456S-459S, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26764325
3.
Evaluation of the Effects of S-Allyl-L-cysteine, S-Methyl-L-cysteine, trans-S-1-Propenyl-L-cysteine, and Their N-Acetylated and S-Oxidized Metabolites on Human CYP Activities.
Biol Pharm Bull
; 39(10): 1701-1707, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27725449
4.
Pharmacokinetics and N-acetylation metabolism of S-methyl-l-cysteine and trans-S-1-propenyl-l-cysteine in rats and dogs.
Xenobiotica
; 46(11): 1017-25, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26887651
5.
Metabolism, excretion, and pharmacokinetics of S-allyl-L-cysteine in rats and dogs.
Drug Metab Dispos
; 43(5): 749-55, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25681129
6.
Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target.
Nat Commun
; 15(1): 5085, 2024 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38877016
7.
The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.
Chem Biol Interact
; 172(1): 11-21, 2008 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18191824
8.
Discovery of WQ-3810: Design, synthesis, and evaluation of 7-(3-alkylaminoazetidin-1-yl)fluoro-quinolones as orally active antibacterial agents.
Eur J Med Chem
; 103: 354-60, 2015 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26363871
9.
In vitro activity of WQ-3810, a novel fluoroquinolone, against multidrug-resistant and fluoroquinolone-resistant pathogens.
Int J Antimicrob Agents
; 44(5): 443-9, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25239276
10.
The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol.
Biochem Pharmacol
; 77(5): 920-31, 2009 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19059219
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