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1.
Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch.
Biochemistry
; 57(9): 1523-1532, 2018 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29412660
2.
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.
J Immunol
; 195(5): 2343-52, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26209628
3.
Pretargeted radioimmunotherapy with the novel anti-oxMIF/HSG bispecific antibody ON105 results in significant tumor regression in murine models of cancer.
Mol Cancer Ther
; 2024 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38833646
4.
Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the ß-sheet structure of MIF.
J Biol Chem
; 287(10): 7446-55, 2012 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22238348
5.
The newly engineered monoclonal antibody ON104, targeting the oxidized Macrophage Migration Inhibitory Factor (oxMIF), ameliorates clinical and histopathological signs of collagen-induced arthritis.
Eur J Pharmacol
; 956: 175997, 2023 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37579967
6.
Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic.
Mol Cancer Ther
; 22(5): 555-569, 2023 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37067909
7.
Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics.
Antibodies (Basel)
; 8(3)2019 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31544852
8.
Pharmacokinetics, disease-modifying activity, and safety of an experimental therapeutic targeting an immunological isoform of macrophage migration inhibitory factor, in rat glomerulonephritis.
Eur J Pharmacol
; 820: 206-216, 2018 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29274331
9.
Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer.
Oncotarget
; 7(45): 73486-73496, 2016 11 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27636991
10.
Human anti-macrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo.
Mol Cancer Ther
; 12(7): 1223-34, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23619302
11.
Higher expression of Fab antibody fragments in a CHO cell line at reduced temperature.
Biotechnol Bioeng
; 84(4): 433-8, 2003 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-14574700
12.
An antibody specific for coagulation factor IX enhances the activity of the intrinsic factor X-activating complex.
J Biol Chem
; 279(39): 40445-50, 2004 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15265864
13.
Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein.
Br J Haematol
; 125(5): 629-37, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15147379
14.
Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13).
Blood
; 100(10): 3626-32, 2002 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12393399
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