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1.
The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens.
Mol Psychiatry
; 2024 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-38822069
2.
Sequestration of Gßγ by deubiquitinated arrestins into the nucleus as a novel desensitization mechanism of G protein-coupled receptors.
Cell Commun Signal
; 21(1): 11, 2023 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-36658650
3.
Unveiling the Differences in Signaling and Regulatory Mechanisms between Dopamine D2 and D3 Receptors and Their Impact on Behavioral Sensitization.
Int J Mol Sci
; 24(7)2023 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37047716
4.
The tyrosine phosphorylation of GRK2 is responsible for activated D2R-mediated insulin resistance.
Biochem Biophys Res Commun
; 628: 40-48, 2022 11 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36063601
5.
New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents.
Arch Toxicol
; 95(4): 1413-1429, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33515270
6.
Roles of the Functional Interaction between Brain Cholinergic and Dopaminergic Systems in the Pathogenesis and Treatment of Schizophrenia and Parkinson's Disease.
Int J Mol Sci
; 22(9)2021 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33919025
7.
GRK2-mediated receptor phosphorylation and Mdm2-mediated ß-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.
Biochem Biophys Res Commun
; 533(3): 383-390, 2020 12 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32962859
8.
Cytoplasmic recruitment of Mdm2 as a common characteristic of G protein-coupled receptors that undergo desensitization.
Biochem Biophys Res Commun
; 530(1): 181-188, 2020 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32828283
9.
A novel molecular mechanism responsible for phosphorylation-independent desensitization of G protein-coupled receptors exemplified by the dopamine D3 receptor.
Biochem Biophys Res Commun
; 528(3): 432-439, 2020 07 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-32505358
10.
ß-Arrestin2 directly or through GRK2 inhibits PKCßII activation in a ubiquitination-dependent manner.
Biochim Biophys Acta Mol Cell Res
; 1865(1): 142-157, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-29054428
11.
Molecular mechanisms involved in epidermal growth factor receptor-mediated inhibition of dopamine D3 receptor signaling.
Biochim Biophys Acta Mol Cell Res
; 1865(9): 1187-1200, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29885323
12.
α4ß2 nicotinic acetylcholine receptor downregulates D3 dopamine receptor expression through protein kinase C activation.
Biochem Biophys Res Commun
; 514(3): 665-671, 2019 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31078264
13.
Design, synthesis and docking study of 4-arylpiperazine carboxamides as monoamine neurotransmitters reuptake inhibitors.
Bioorg Med Chem
; 26(14): 4127-4135, 2018 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30007567
14.
Design, synthesis, and systematic evaluation of 4-arylpiperazine- and 4-benzylpiperidine napthyl ethers as inhibitors of monoamine neurotransmitters reuptake.
Bioorg Med Chem
; 26(20): 5538-5546, 2018 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30293797
15.
RalA employs GRK2 and ß-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.
Biochim Biophys Acta
; 1863(8): 2072-83, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27188791
16.
Palmitoylation on the carboxyl terminus tail is required for the selective regulation of dopamine D2 versus D3 receptors.
Biochim Biophys Acta
; 1858(9): 2152-2162, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27349735
17.
Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors.
Biochim Biophys Acta
; 1863(1): 77-90, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26477566
18.
The EGF receptor inhibits the signaling of dopamine D3 receptor through the phosphorylation of GRK2 on tyrosine residues.
Biochem Biophys Res Commun
; 489(4): 515-522, 2017 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28579429
19.
Design, synthesis and in vitro activity of 1,4-disubstituted piperazines and piperidines as triple reuptake inhibitors.
Bioorg Med Chem
; 25(7): 2266-2276, 2017 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28274674
20.
Triple reuptake inhibitors: Design, synthesis and structure-activity relationship of benzylpiperidine-tetrazoles.
Bioorg Med Chem
; 25(20): 5278-5289, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28807575