Detalles de la búsqueda
1.
Synthesis of 2,3-Benzotropones via Palladium(II)-Catalyzed Aerobic Dehydrogenation from 1-Benzosuberones and Sequential Diels-Alder Reaction to Yield Benzobicyclo[3.2.2]nonenones.
J Org Chem
; 89(5): 3102-3110, 2024 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38364274
2.
Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability.
Bioorg Med Chem
; 100: 117588, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38295487
3.
Enhancing polyethylene degradation: a novel bioprocess approach using Acinetobacter nosocomialis pseudo-resting cells.
Appl Microbiol Biotechnol
; 108(1): 86, 2024 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38189951
4.
Identification of novel pyrrolopyrimidine and pyrrolopyridine derivatives as potent ENPP1 inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 2434-2451, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36069240
5.
Identification of ortho catechol-containing isoflavone as a privileged scaffold that directly prevents the aggregation of both amyloid ß plaques and tau-mediated neurofibrillary tangles and its in vivo evaluation.
Bioorg Chem
; 113: 105022, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34098397
6.
Chemical Degradation of Androgen Receptor (AR) Using Bicalutamide Analog-Thalidomide PROTACs.
Molecules
; 26(9)2021 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33926033
7.
Ginger and 6-shogaol protect intestinal tight junction and enteric dopaminergic neurons against 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine in mice.
Nutr Neurosci
; 23(6): 455-464, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30230979
8.
Synthesis of Flavanones via Palladium(II)-Catalyzed One-Pot ß-Arylation of Chromanones with Arylboronic Acids.
J Org Chem
; 84(16): 10012-10023, 2019 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31322349
9.
A Novel and Selective p38 Mitogen-Activated Protein Kinase Inhibitor Attenuates LPS-Induced Neuroinflammation in BV2 Microglia and a Mouse Model.
Neurochem Res
; 43(12): 2362-2371, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30327995
10.
Bardoxolone Methyl Suppresses Hepatitis B Virus Large Surface Protein Variant W4P-Related Carcinogenesis and Hepatocellular Carcinoma Cell Proliferation Via the Inhibition of Signal Transducer and Activator of Transcription 3 Signaling.
Pharmacology
; 102(1-2): 105-113, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29953997
11.
Recent Advances in Synthesis of 4-Arylcoumarins.
Molecules
; 23(10)2018 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30241375
12.
An Effective Antiviral Approach Targeting Hepatitis B Virus with NJK14047, a Novel and Selective Biphenyl Amide p38 Mitogen-Activated Protein Kinase Inhibitor.
Antimicrob Agents Chemother
; 61(8)2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28559272
13.
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells.
Bioorg Med Chem Lett
; 27(11): 2613-2616, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28408221
14.
Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease.
Molecules
; 22(8)2017 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28767069
15.
A novel p38 mitogen activated protein kinase (MAPK) specific inhibitor suppresses respiratory syncytial virus and influenza A virus replication by inhibiting virus-induced p38 MAPK activation.
Biochem Biophys Res Commun
; 477(3): 311-6, 2016 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-27346133
16.
Identification and Structural Analysis of New Nrf2 Activators by Mechanism-Based Chemical Transformation of 15-Deoxy-Δ12, 14 -PGJ2.
Chembiochem
; 17(20): 1900-1904, 2016 10 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27453569
17.
Identification of novel estrogen receptor (ER) agonists that have additional and complementary anti-cancer activities via ER-independent mechanism.
Bioorg Med Chem Lett
; 26(7): 1844-8, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26905830
18.
A versatile approach to flavones via a one-pot Pd(II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones.
Org Biomol Chem
; 14(2): 777-784, 2016 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26592753
19.
Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate.
Bioconjug Chem
; 26(11): 2216-22, 2015 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-25945727
20.
Synthesis and biological evaluation of N-cyclopropylbenzamide-benzophenone hybrids as novel and selective p38 mitogen activated protein kinase (MAPK) inhibitors.
Bioorg Med Chem Lett
; 25(17): 3694-8, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26115577