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1.
NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension.
BMC Pulm Med
; 20(1): 85, 2020 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32252727
2.
Differential expression of the TPα and TPß isoforms of the human T Prostanoid receptor during chronic inflammation of the prostate: Role for FOXP1 in the transcriptional regulation of TPß during monocyte-macrophage differentiation.
Exp Mol Pathol
; 110: 104277, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31271729
3.
Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor.
Biochim Biophys Acta Mol Cell Res
; 1864(10): 1819-1832, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28739266
4.
Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol.
Biochim Biophys Acta
; 1859(10): 1333-51, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27365208
5.
Regulation of protein kinase C-related kinase (PRK) signalling by the TPα and TPß isoforms of the human thromboxane A2 receptor: Implications for thromboxane- and androgen- dependent neoplastic and epigenetic responses in prostate cancer.
Biochim Biophys Acta Mol Basis Dis
; 1863(4): 838-856, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28108419
6.
Regulated expression of the TPß isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer.
Biochim Biophys Acta Mol Basis Dis
; 1863(12): 3153-3169, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28890397
7.
Transcriptional regulation of the human thromboxane A2 receptor gene by Wilms' tumor (WT)1 and hypermethylated in cancer (HIC) 1 in prostate and breast cancers.
Biochim Biophys Acta
; 1839(6): 476-92, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24747176
8.
Prostacyclin receptors: Transcriptional regulation and novel signalling mechanisms.
Prostaglandins Other Lipid Mediat
; 121(Pt A): 70-82, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25936507
9.
Investigation of the mechanisms of G protein: Effector coupling by the human and mouse prostacyclin receptors. Identification of critical species-dependent differences.
J Biol Chem
; 293(31): 12285, 2018 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30076257
10.
Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to Gs-, to Gi-, and to Gq-coupled effector signaling.
J Biol Chem
; 293(28): 11046, 2018 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30006385
11.
Interaction of the human prostacyclin receptor with Rab11. Characterization of a novel Rab11 binding domain within α-helix 8 that is regulated by palmitoylation.
J Biol Chem
; 293(31): 12287, 2018 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30076259
12.
Identification of an interaction between the TPα and TPß isoforms of the human thromboxane A2 receptor with protein kinase C-related kinase (PRK) 1. Implications for prostate cancer.
J Biol Chem
; 293(31): 12286, 2018 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30076258
13.
Regulation of the human prostacyclin receptor gene in megakaryocytes: major roles for C/EBPδ and PU.1.
Biochim Biophys Acta
; 1819(5): 428-45, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22381139
14.
Interaction of the human prostacyclin receptor and the NHERF4 family member intestinal and kidney enriched PDZ protein (IKEPP).
Biochim Biophys Acta
; 1823(10): 1998-2012, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22884631
15.
Evaluation of NTP42, a novel thromboxane receptor antagonist, in a first-in-human phase I clinical trial.
Front Pharmacol
; 14: 1296188, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38178863
16.
Regulation of the human prostacyclin receptor gene by the cholesterol-responsive SREBP1.
J Lipid Res
; 53(11): 2390-404, 2012 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22969152
17.
Palmitoylation of the human prostacyclin receptor. FUNCTIONAL IMPLICATIONS OF PALMITOYLATION AND ISOPRENYLATION.
J Biol Chem
; 291(37): 19259, 2016 09 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27613955
18.
The α, but not the ß, isoform of the human thromboxane A2 receptor is a target for nitric oxide-mediated desensitization. INDEPENDENT MODULATION OF TPα SIGNALING BY NITRIC OXIDE AND PROSTACYCLIN.
J Biol Chem
; 291(37): 19260, 2016 09 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27613956
19.
Identification of an interaction between the TPalpha and TPbeta isoforms of the human thromboxane A2 receptor with protein kinase C-related kinase (PRK) 1: implications for prostate cancer.
J Biol Chem
; 286(17): 15440-57, 2011 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-21357687
20.
Identification of a novel endoplasmic reticulum export motif within the eighth α-helical domain (α-H8) of the human prostacyclin receptor.
Biochim Biophys Acta
; 1808(4): 1202-18, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21223948