Detalles de la búsqueda
1.
Quantitative Analysis of mRNA and Protein Expression Levels of Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoforms in the Human Intestine.
Drug Metab Dispos
; 51(12): 1569-1577, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37722844
2.
Regional Transcriptomics and Proteomics of Pharmacokinetics-Related Genes in Human Intestine.
Mol Pharm
; 20(6): 2876-2890, 2023 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37132462
3.
Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10.
J Pharmacol Sci
; 150(1): 41-48, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35926947
4.
[Perforin gene mutation in middle-age onset hemophagocytic lymphohistiocytosis].
Rinsho Ketsueki
; 63(12): 1633-1638, 2022.
Artículo
en Japonés
| MEDLINE | ID: mdl-36653135
5.
Comparison of culture media for human intestinal organoids from the viewpoint of pharmacokinetic studies.
Biochem Biophys Res Commun
; 566: 115-122, 2021 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34119823
6.
In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics.
Drug Metab Dispos
; 49(3): 221-232, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33384384
7.
[BCR-ABL1-positive myelodysplastic syndrome with neutropenia and anemia treated successfully with imatinib mesylate].
Rinsho Ketsueki
; 61(5): 455-461, 2020.
Artículo
en Japonés
| MEDLINE | ID: mdl-32507808
8.
Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species.
Chem Res Toxicol
; 28(1): 103-15, 2015 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25489797
9.
Brain penetration of WEB 2086 (Apafant) and dantrolene in Mdr1a (P-glycoprotein) and Bcrp knockout rats.
Drug Metab Dispos
; 42(10): 1761-5, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25053619
10.
In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold.
Drug Metab Dispos
; 42(2): 257-63, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24212378
11.
Impact of endogenous esterase activity on in vitro p-glycoprotein profiling of dabigatran etexilate in Caco-2 monolayers.
Drug Metab Dispos
; 42(2): 250-6, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24212377
12.
Establishment of human intestinal organoids derived from commercially available cryopreserved intestinal epithelium and evaluation for pharmacokinetic study.
Drug Metab Pharmacokinet
; 54: 100532, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38064926
13.
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Drug Metab Dispos
; 41(1): 149-58, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23073734
14.
Establishment of MDR1-knockout human enteroids for pharmaceutical application.
Drug Metab Pharmacokinet
; 48: 100476, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36521426
15.
Comparison of human biopsy-derived and human iPS cell-derived intestinal organoids established from a single individual.
Drug Metab Pharmacokinet
; 48: 100482, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36653202
16.
Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities.
Drug Metab Dispos
; 40(1): 83-92, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21994437
17.
CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.
Proc Natl Acad Sci U S A
; 106(37): 15744-9, 2009 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19805222
18.
Advanced glycation end products inhibitors from Alpinia zerumbet rhizomes.
Food Chem
; 129(3): 709-15, 2011 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25212289
19.
Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research.
Mol Ther Methods Clin Dev
; 22: 263-278, 2021 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34485610
20.
A case of AITL complicated by EBV-positive B cell and monoclonal plasma cell proliferation and effectively treated with lenalidomide.
Int J Hematol
; 109(4): 499-504, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30604313