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1.
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship.
Bioorg Med Chem
; 19(3): 1242-55, 2011 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21236687
2.
Novel tight-binding inhibitory factor-kappaB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation.
J Pharmacol Exp Ther
; 330(2): 377-88, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19478133
3.
Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IkappaB kinase-2 (IKK-2) target safety and efficacy.
J Pharm Sci
; 99(3): 1278-87, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19743500
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