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1.
Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments.
Cancer Sci
; 115(6): 1763-1777, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38527308
2.
Emicizumab enhances thrombus formation in vitro under high shear flow conditions in whole blood from patients with type 1 and type 3 von Willebrand disease.
Haemophilia
; 28(5): 694-701, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35478475
3.
Emicizumab improves thrombus formation of type 2A von willebrand disease under high shear condition.
Haemophilia
; 27(2): e194-e203, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33555083
4.
Emicizumab-mediated haemostatic function in patients with haemophilia A is down-regulated by activated protein C through inactivation of activated factor V.
Br J Haematol
; 183(2): 257-266, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30125997
5.
Anti-factor IXa/X bispecific antibody ACE910 prevents joint bleeds in a long-term primate model of acquired hemophilia A.
Blood
; 124(20): 3165-71, 2014 Nov 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-25274508
6.
Reduced plasma factor X is associated with a lack of response to recombinant activated factor VII in patients with hemophilia A and inhibitor, but does not impair emicizumab-driven hemostasis in vitro.
Thromb Res
; 237: 37-45, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38547693
7.
NXT007-mediated hemostatic potential is suppressed by activated protein C-catalyzed inactivation of activated factor V.
Res Pract Thromb Haemost
; 8(1): 102271, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38115953
8.
Emicizumab-mediated hemostatic function assessed by thrombin generation assay in an in vitro model of factor VIII-depleted thrombophilia plasma.
Int J Hematol
; 119(2): 109-118, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38112996
9.
A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a nonhemophilic state.
J Thromb Haemost
; 22(2): 430-440, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37940048
10.
Engineering CD3/CD137 dual specificity into a DLL3-targeted T-cell engager enhances T-cell infiltration and efficacy against small cell lung cancer.
Cancer Immunol Res
; 2024 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38558120
11.
Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer.
Cancer Immunol Res
; : OF1-OF12, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38563577
12.
Efficient production of bispecific antibody by FAST-IgTM and its application to NXT007 for the treatment of hemophilia A.
MAbs
; 15(1): 2222441, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37339067
13.
Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease.
Nat Commun
; 14(1): 8502, 2023 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38135691
14.
Tumor-infiltrating Leukocyte Profiling Defines Three Immune Subtypes of NSCLC with Distinct Signaling Pathways and Genetic Alterations.
Cancer Res Commun
; 3(6): 1026-1040, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37377611
15.
Determination of starting dose of the T cell-redirecting bispecific antibody ERY974 targeting glypican-3 in first-in-human clinical trial.
Sci Rep
; 12(1): 12312, 2022 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35853994
16.
Combination of T cell-redirecting bispecific antibody ERY974 and chemotherapy reciprocally enhances efficacy against non-inflamed tumours.
Nat Commun
; 13(1): 5265, 2022 09 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36071036
17.
Emicizumab Augments Thrombus Formation in Whole Blood from Patients with Hemophilia A under High Shear Flow Conditions.
Thromb Haemost
; 121(3): 279-286, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-32906155
18.
Activated factor VIII-mimicking effect by emicizumab on thrombus formation in type 2N von Willebrand disease under high shear flow conditions.
Thromb Res
; 198: 7-16, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33248318
19.
Novel myostatin-specific antibody enhances muscle strength in muscle disease models.
Sci Rep
; 11(1): 2160, 2021 01 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33495503
20.
Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation.
Cancer Discov
; 11(1): 158-175, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32847940