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1.
Safety, tolerability, pharmacokinetics and effect on serum uric acid of the myeloperoxidase inhibitor AZD4831 in a randomized, placebo-controlled, phase I study in healthy volunteers.
Br J Clin Pharmacol
; 85(4): 762-770, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30618054
2.
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator.
Br J Clin Pharmacol
; 84(7): 1486-1493, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29468715
3.
Estimands: discussion points from the PSI estimands and sensitivity expert group.
Pharm Stat
; 16(1): 6-11, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26997517
4.
Early Clinical Experience With AZD4831, A Novel Myeloperoxidase Inhibitor, Developed for Patients With Heart Failure With Preserved Ejection Fraction.
Clin Transl Sci
; 14(3): 812-819, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32770730
5.
Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability.
Clin Pharmacol Drug Dev
; 9(3): 411-421, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31793171
6.
Design and rationale of FLAVOUR: A phase IIa efficacy study of the 5-lipoxygenase activating protein antagonist AZD5718 in patients with recent myocardial infarction.
Contemp Clin Trials Commun
; 19: 100629, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32875138
7.
Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial.
Mol Ther Methods Clin Dev
; 18: 464-472, 2020 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32728595
8.
Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study.
Clin Transl Sci
; 13(2): 275-283, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31584739
9.
Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.
Nat Commun
; 10(1): 871, 2019 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30787295
10.
Initial Clinical Experience with AZD5718, a Novel Once Daily Oral 5-Lipoxygenase Activating Protein Inhibitor.
Clin Transl Sci
; 11(3): 330-338, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29517132
11.
Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.
PLoS One
; 13(12): e0208998, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30557325
12.
Effects of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, and dalteparin on the endogenous thrombin potential in venous blood from healthy male subjects.
Blood Coagul Fibrinolysis
; 14(5): 457-62, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12851531
13.
The metabotropic glutamate mGluR5 receptor agonist CHPG stimulates food intake.
Neuroreport
; 21(10): 704-8, 2010 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20505551
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