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1.
A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia.
Blood
; 129(24): 3165-3174, 2017 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28336527
2.
Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis.
Blood
; 130(9): 1132-1143, 2017 08 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-28630120
3.
Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds.
BMC Cancer
; 15: 910, 2015 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26573568
4.
Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.
Mol Ther
; 19(12): 2186-200, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21971424
5.
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Oncoimmunology
; 11(1): 2141007, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36352891
6.
Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents.
Oncotarget
; 9(56): 30773-30786, 2018 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30112106
7.
Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death.
Oncotarget
; 9(39): 25529-25544, 2018 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29876006
8.
Clinical Dosing Regimen of Selinexor Maintains Normal Immune Homeostasis and T-cell Effector Function in Mice: Implications for Combination with Immunotherapy.
Mol Cancer Ther
; 16(3): 428-439, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28148714
9.
The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors.
Mol Cancer Ther
; 16(3): 417-427, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28148715
10.
A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds.
Oncotarget
; 7(2): 1863-77, 2016 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-26654943
11.
Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.
Oncotarget
; 7(48): 78883-78895, 2016 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-27713151
12.
In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.
J Am Coll Cardiol
; 63(15): 1556-66, 2014 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-24361318
13.
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity.
Nat Commun
; 5: 4277, 2014 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24969323
14.
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Mol Ther Nucleic Acids
; 1: e4, 2012 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-23344621
15.
Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes.
J Immunol
; 177(8): 4962-5, 2006 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17015677
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