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1.
ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS.
Front Neurosci
; 18: 1348157, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38389786
2.
Non-Redundant Roles of T Cell Costimulation Pathways in Inflammatory Arthritis Revealed by Dual Blockade of ICOS and CD28 with Acazicolcept (ALPN-101).
Arthritis Rheumatol
; 75(8): 1344-1356, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36862144
3.
Povetacicept, an Enhanced Dual APRIL/BAFF Antagonist That Modulates B Lymphocytes and Pathogenic Autoantibodies for the Treatment of Lupus and Other B Cell-Related Autoimmune Diseases.
Arthritis Rheumatol
; 75(7): 1187-1202, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36705554
4.
The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.
Nat Commun
; 13(1): 1790, 2022 04 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35379805
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