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1.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Toxicol Appl Pharmacol
; 394: 114961, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32209365
2.
An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities.
Toxicol Appl Pharmacol
; 329: 121-127, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28546047
3.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Toxicol Appl Pharmacol
; 395: 114983, 2020 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32247767
4.
Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA.
J Med Chem
; 64(20): 15214-15249, 2021 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34614347
5.
Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo.
Microorganisms
; 9(3)2021 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33801811
6.
Novel bacterial topoisomerase inhibitors derived from isomannide.
Eur J Med Chem
; 199: 112324, 2020 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32402932
7.
Myocardial contrast echocardiography can be used to assess the microvascular response to vascular endothelial growth factor-121.
Circulation
; 105(6): 759-65, 2002 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-11839634
8.
Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity.
Mol Pharmacol
; 68(3): 876-84, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15976038
9.
Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics.
J Pharmacol Exp Ther
; 302(1): 320-7, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12065733
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