Detalles de la búsqueda
1.
Discovery of (E)-3-(4-chlorophenyl)-N-(5-hydroxypentyl)acrylamide among N-substituted cinnamamide derivatives as a novel cosmetic ingredient for hyperpigmentation.
Bioorg Chem
; 150: 107533, 2024 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38878750
2.
Comparative study on ABCB1-dependent efflux of anthracyclines and their metabolites: consequences for cancer resistance.
Xenobiotica
; 53(6-7): 507-514, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37753851
3.
In Silico and In Vitro Assessment of Carbonyl Reductase 1 Inhibition Using ASP9521-A Potent Aldo-Keto Reductase 1C3 Inhibitor with the Potential to Support Anticancer Therapy Using Anthracycline Antibiotics.
Molecules
; 28(9)2023 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37175180
4.
In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione.
Toxicol Appl Pharmacol
; 457: 116318, 2022 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36414119
5.
Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model EpiskinTM: Perspectives for Application as Potential Sunscreen Agents.
Molecules
; 27(6)2022 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35335215
6.
Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer.
Invest New Drugs
; 39(2): 538-563, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33159673
7.
Synthesis and in vitro evaluation of anti-inflammatory, antioxidant, and anti-fibrotic effects of new 8-aminopurine-2,6-dione-based phosphodiesterase inhibitors as promising anti-asthmatic agents.
Bioorg Chem
; 117: 105409, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34749117
8.
Cinnamic Acid Derivatives as Cardioprotective Agents against Oxidative and Structural Damage Induced by Doxorubicin.
Int J Mol Sci
; 22(12)2021 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34207549
9.
Anticonvulsant and analgesic in neuropathic pain activity in a group of new aminoalkanol derivatives.
Bioorg Med Chem Lett
; 30(16): 127325, 2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32631530
10.
The Involvement of Xanthone and (E)-Cinnamoyl Chromophores for the Design and Synthesis of Novel Sunscreening Agents.
Int J Mol Sci
; 22(1)2020 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-33375127
11.
A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-ß Signaling and Activation of cAMP/PKA Signaling.
Int J Mol Sci
; 21(11)2020 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32503342
12.
S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy.
Int J Mol Sci
; 21(12)2020 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-32575479
13.
Improving Activity of New Arylurea Agents against Multidrug-Resistant and Biofilm-Producing Staphylococcus epidermidis.
ACS Med Chem Lett
; 15(3): 369-375, 2024 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38505856
14.
Antidepressant pharmaceuticals in aquatic systems, individual-level ecotoxicological effects: growth, survival and behavior.
Aquat Toxicol
; 260: 106554, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37167880
15.
In silico and in vitro evaluation of a safety profile of a cosmetic ingredient: 4-methoxychalcone (4-MC).
Toxicol In Vitro
; 93: 105696, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37722549
16.
Saponin Fraction CIL1 from Lysimachia ciliata L. Enhances the Effect of a Targeted Toxin on Cancer Cells.
Pharmaceutics
; 15(5)2023 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37242592
17.
Inhaled pan-phosphodiesterase inhibitors ameliorate ovalbumin-induced airway inflammation and remodeling in murine model of allergic asthma.
Int Immunopharmacol
; 119: 110264, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37159965
18.
KM-408, a novel phenoxyalkyl derivative as a potential anticonvulsant and analgesic compound for the treatment of neuropathic pain.
Pharmacol Rep
; 75(1): 128-165, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36401763
19.
Pan-Phosphodiesterase Inhibitors Attenuate TGF-ß-Induced Pro-Fibrotic Phenotype in Alveolar Epithelial Type II Cells by Downregulating Smad-2 Phosphorylation.
Pharmaceuticals (Basel)
; 15(4)2022 Mar 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35455420
20.
Cinnamamide derivatives with 4-hydroxypiperidine moiety enhance effect of doxorubicin to cancer cells and protect cardiomyocytes against drug-induced toxicity through CBR1 inhibition mechanism.
Life Sci
; 305: 120777, 2022 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35792180