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1.
Targeted delivery to macrophages and dendritic cells by chemically modified mannose ligand-conjugated siRNA.
Nucleic Acids Res
; 50(9): 4840-4859, 2022 05 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35524566
2.
Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold.
Bioorg Med Chem
; 27(22): 115122, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31623970
3.
The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.
Hum Mol Genet
; 25(2): 245-53, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26604152
4.
Low-dose immunoglobulin G is not associated with mortality in patients with sepsis and septic shock.
Crit Care
; 21(1): 181, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28701223
5.
Quantitative investigation of the brain-to-cerebrospinal fluid unbound drug concentration ratio under steady-state conditions in rats using a pharmacokinetic model and scaling factors for active efflux transporters.
Drug Metab Dispos
; 42(6): 983-9, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24644297
6.
Population pharmacokinetics of PEGylated liposomal CPT-11 (IHL-305) in patients with advanced solid tumors.
Eur J Clin Pharmacol
; 69(12): 2073-81, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23989300
7.
Heat stroke management during the COVID-19 pandemic: Recommendations from the experts in Japan (2nd edition).
Acute Med Surg
; 10(1): e827, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37056485
8.
Species differences in the pharmacokinetics of KW-7158 [(2S)-(+)-3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide]: formation of hydrolyzed metabolite in human and animals.
Xenobiotica
; 42(7): 649-59, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22324379
9.
Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.
J Pharmacol Exp Ther
; 339(3): 935-44, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21934030
10.
Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone.
J Pharmacol Exp Ther
; 333(3): 788-96, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20304939
11.
Characteristics, treatments, and outcomes of severe sepsis of 3195 ICU-treated adult patients throughout Japan during 2011-2013.
J Intensive Care
; 4: 44, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27413534
12.
Antithrombin Supplementation and Mortality in Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study.
Shock
; 46(6): 623-631, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27548460
13.
Design of a pH-sensitive polymeric carrier for drug release and its application in cancer therapy.
Clin Cancer Res
; 10(7): 2545-50, 2004 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15073135
14.
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors.
Int J Nanomedicine
; 10: 1201-9, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25709442
15.
Construction of recombinant herpes simplex virus type I expressing green fluorescent protein without loss of any viral genes.
Microbes Infect
; 6(5): 485-93, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15109964
16.
The targeting of anionized polyvinylpyrrolidone to the renal system.
Biomaterials
; 25(18): 4309-15, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15046921
17.
The use of PVP as a polymeric carrier to improve the plasma half-life of drugs.
Biomaterials
; 25(16): 3259-66, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-14980420
18.
Effective accumulation of poly(vinylpyrrolidone-co-vinyl laurate) into the spleen.
J Biomed Mater Res A
; 70(2): 219-23, 2004 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15227666
19.
[3q21q26 syndrome with minor-BCR/ABL type Ph chromosome].
Rinsho Ketsueki
; 44(12): 1166-71, 2003 Dec.
Artículo
en Japonés
| MEDLINE | ID: mdl-14978933
20.
Potentials and limitations of nonclinical safety assessment for predicting clinical adverse drug reactions: correlation analysis of 142 approved drugs in Japan.
J Toxicol Sci
; 38(4): 581-98, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23824014