Detalles de la búsqueda
1.
Synthesis and anti-cancer potential of the positional isomers of NOSH-aspirin (NBS-1120) a dual nitric oxide and hydrogen sulfide releasing hybrid.
Bioorg Med Chem Lett
; 25(20): 4677-82, 2015 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26323873
2.
Nitric Oxide-Releasing Aspirin Suppresses NF-κB Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo.
Molecules
; 20(7): 12481-99, 2015 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-26184135
3.
NOSH-aspirin (NBS-1120), a novel nitric oxide and hydrogen sulfide releasing hybrid, attenuates neuroinflammation induced by microglial and astrocytic activation: a new candidate for treatment of neurodegenerative disorders.
Glia
; 61(10): 1724-34, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23918470
4.
Positional isomers of aspirin are equally potent in inhibiting colon cancer cell growth: differences in mode of cyclooxygenase inhibition.
J Pharmacol Exp Ther
; 345(1): 85-94, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23349335
5.
NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model.
Biochem Biophys Res Commun
; 419(3): 523-8, 2012 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-22366248
6.
Synthesis and biological activity of acetyl-protected hydroxybenzyl diethyl phosphates (EHBP) as potential chemotherapeutic agents.
Bioorg Med Chem Lett
; 21(23): 7146-50, 2011 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22001089
7.
NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-κB, iNOS, caspase-3 and ROS.
Biochem Pharmacol
; 176: 113857, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32061771
8.
Gastrointestinal safety, chemotherapeutic potential, and classic pharmacological profile of NOSH-naproxen (AVT-219) a dual NO- and H2S-releasing hybrid.
Pharmacol Res Perspect
; 4(2): e00224, 2016 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27069635
9.
NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties.
Redox Biol
; 6: 287-296, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26298203
10.
NOSH-Aspirin Inhibits Colon Cancer Cell Growth: Effects Of Positional Isomerism.
Redox Biol
; 5: 421, 2015 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28162291
11.
NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications.
Biochem Pharmacol
; 98(4): 564-72, 2015 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26394025
12.
Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-κB signaling.
Drug Des Devel Ther
; 9: 4873-82, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26346117
13.
Positional isomerism markedly affects the growth inhibition of colon cancer cells by NOSH-aspirin: COX inhibition and modeling.
Redox Biol
; 6: 318-325, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26319435
14.
Synthesis and biological activity of NOSH-naproxen (AVT-219) and NOSH-sulindac (AVT-18A) as potent anti-inflammatory agents with chemotherapeutic potential.
Medchemcomm
; 4(11)2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24273639
15.
Hydrogen sulfide-releasing aspirin inhibits the growth of leukemic Jurkat cells and modulates ß-catenin expression.
Leuk Res
; 37(10): 1302-8, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23896061
16.
NOSH-Aspirin: A Novel Nitric Oxide-Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals.
ACS Med Chem Lett
; 3(3): 257-262, 2012 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22916316
17.
Hydrogen sulfide-releasing aspirin suppresses NF-κB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo.
Biochem Pharmacol
; 83(6): 723-32, 2012 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22209867
18.
Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo.
Biochem Pharmacol
; 83(6): 733-40, 2012 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22209714
19.
Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect.
Biochem Pharmacol
; 83(6): 715-22, 2012 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22222427
20.
NO-releasing NSAIDs suppress NF-κB signaling in vitro and in vivo through S-nitrosylation.
Cancer Lett
; 298(2): 204-11, 2010 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-20674154