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1.
Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE-/- mouse model.
J Appl Toxicol
; 41(10): 1598-1619, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33825214
2.
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague-Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
Arch Toxicol
; 94(6): 2179-2206, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32367274
3.
Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.
Inhal Toxicol
; 30(13-14): 553-567, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30849254
4.
Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S82-S92, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27866933
5.
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S59-S81, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27793746
6.
Evaluation of the Tobacco Heating System 2.2. Part 7: Systems toxicological assessment of a mentholated version revealed reduced cellular and molecular exposure effects compared with mentholated and non-mentholated cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S123-S138, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27818347
7.
Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S93-S122, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27818348
8.
Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.
Inflamm Res
; 64(7): 471-86, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25962837
9.
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology.
Inhal Toxicol
; 27(9): 405-31, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26295358
10.
Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2.
J Biol Chem
; 286(22): 19410-6, 2011 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-21493713
11.
Systems biology approach highlights mechanistic differences between Crohn's disease and ulcerative colitis.
Sci Rep
; 11(1): 11519, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34075172
12.
Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.
J Inflamm (Lond)
; 17: 29, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32855621
13.
Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein.
Mol Cell Biol
; 26(16): 5994-6004, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16880511
14.
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.
Food Chem Toxicol
; 116(Pt B): 388-413, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29654848
15.
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.
Food Chem Toxicol
; 115: 284-301, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29545142
16.
Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.
Food Chem Toxicol
; 109(Pt 1): 315-332, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28882640
17.
Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™).
Gene Regul Syst Bio
; 8: 45-61, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24596455
18.
Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression.
BMC Res Notes
; 7: 302, 2014 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24886675
19.
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
Food Chem Toxicol
; 68: 204-17, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24632068
20.
The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.
Cell
; 123(3): 409-21, 2005 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-16269333
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