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1.
Design and synthesis of oligo-lipidated arginyl peptide (OLAP) dimers with enhanced physicochemical activity, peptide stability and their antimicrobial actions against MRSA infections.
Amino Acids
; 50(10): 1329-1345, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30066172
2.
Recent advances in synthetic lipopeptides as anti-microbial agents: designs and synthetic approaches.
Amino Acids
; 49(10): 1653-1677, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28823054
3.
A novel fragment based strategy for membrane active antimicrobials against MRSA.
Biochim Biophys Acta
; 1848(4): 1023-31, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25582665
4.
Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting.
Biochim Biophys Acta
; 1828(2): 834-44, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22982495
5.
Stapled ß-Hairpin Antimicrobial Peptides with Improved Stability and Activity against Drug-Resistant Gram-Negative Bacteria.
J Med Chem
; 66(13): 8498-8509, 2023 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37357499
6.
Manipulating turn residues on de novo designed ß-hairpin peptides for selectivity against drug-resistant bacteria.
Acta Biomater
; 135: 214-224, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34506975
7.
Antimicrobial activity profiles of Amphiphilic Xanthone derivatives are a function of their molecular Oligomerization.
Biochim Biophys Acta Biomembr
; 1860(11): 2281-2298, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29782818
8.
Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design.
Front Neurosci
; 11: 73, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28261050
9.
Semisynthesis and Biological Evaluation of Xanthone Amphiphilics as Selective, Highly Potent Antifungal Agents to Combat Fungal Resistance.
J Med Chem
; 60(24): 10135-10150, 2017 12 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29155590
10.
Symmetrically Substituted Xanthone Amphiphiles Combat Gram-Positive Bacterial Resistance with Enhanced Membrane Selectivity.
J Med Chem
; 60(4): 1362-1378, 2017 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28122182
11.
Semisynthetic Flavone-Derived Antimicrobials with Therapeutic Potential against Methicillin-Resistant Staphylococcus aureus (MRSA).
J Med Chem
; 60(14): 6152-6165, 2017 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28636355
12.
Nonpeptidic Amphiphilic Xanthone Derivatives: Structure-Activity Relationship and Membrane-Targeting Properties.
J Med Chem
; 59(1): 171-93, 2016 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26681070
13.
Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties.
Eur J Med Chem
; 123: 684-703, 2016 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27517813
14.
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization.
J Med Chem
; 58(16): 6533-48, 2015 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26214729
15.
Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections.
J Med Chem
; 58(2): 739-52, 2015 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-25474410
16.
Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity.
J Med Chem
; 56(6): 2359-73, 2013 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23441632
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