Detalles de la búsqueda
1.
Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aß uptake in astrocytes.
J Lipid Res
; 65(3): 100510, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38280459
2.
A novel monoclonal antibody with improved FcγR blocking ability demonstrated non-inferior efficacy compared to IVIG in cynomolgus monkey ITP model at considerably lower dose.
Clin Exp Immunol
; 211(1): 23-30, 2023 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36480334
3.
Discovery and mechanistic study of thiazole-4-acylsulfonamide derivatives as potent and orally active ChemR23 inhibitors with a long-acting effect in cynomolgus monkeys.
Bioorg Med Chem
; 56: 116587, 2022 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35063894
4.
The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors.
Bioorg Med Chem
; 28(17): 115622, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32773087
5.
The discovery and optimization of a series of 2-aminobenzoxazole derivatives as ChemR23 inhibitors.
Bioorg Med Chem
; 27(21): 115091, 2019 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31521459
6.
Functional analysis of juxta- and intra-membrane domains of murine APP by genome editing in Neuro2a cells.
Biochem Biophys Res Commun
; 501(4): 1023-1028, 2018 07 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29777707
7.
Corrigendum to "Discovery and mechanistic study of thiazole-4-acylsulfonamide derivatives as potent and orally active ChemR23 inhibitors with a long-acting effect in cynomolgus monkeys" [Bioorg. Med. Chem. 56 (2022) 116587].
Bioorg Med Chem
; 59: 116678, 2022 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35210135
8.
Internalization of CCR4 and inhibition of chemotaxis by K777, a potent and selective CCR4 antagonist.
Pharmacology
; 91(5-6): 305-13, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23751403
9.
The Pursuit of the "Inside" of the Amyloid Hypothesis-Is C99 a Promising Therapeutic Target for Alzheimer's Disease?
Cells
; 12(3)2023 01 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-36766796
10.
Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer's disease.
iScience
; 25(3): 103869, 2022 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35243232
11.
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.
J Pharmacol Sci
; 112(2): 203-13, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20134116
12.
Inhibitory effect of the new orally active CCR4 antagonist K327 on CCR4+CD4+ T cell migration into the lung of mice with ovalbumin-induced lung allergic inflammation.
Pharmacology
; 84(3): 171-82, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19713720
13.
Effect of olopatadine hydrochloride, an anti-histamine drug, on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.
Int Immunopharmacol
; 8(6): 916-21, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18442798
14.
Role of Th2 responses in the development of allergen-induced airway remodelling in a murine model of allergic asthma.
Br J Pharmacol
; 138(5): 912-20, 2003 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-12642393
15.
Effect of MX-68 on airway inflammation and hyperresponsiveness in mice and guinea-pigs.
J Pharm Pharmacol
; 56(2): 187-96, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15005877
16.
Role of prostaglandin I2 in airway remodeling induced by repeated allergen challenge in mice.
Am J Respir Cell Mol Biol
; 29(3 Pt 1): 314-20, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12676807
17.
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice.
Am J Respir Cell Mol Biol
; 31(1): 62-8, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-14975941
Resultados
1 -
17
de 17
1
Próxima >
>>