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1.
Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.
Sci Rep
; 8(1): 15458, 2018 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30337562
2.
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.
J Med Chem
; 60(23): 9599-9616, 2017 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29072452
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