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1.
NF-κB activation mediates LPS-or zymosan-induced hypotension and inflammation reversed by BAY61-3606, a selective Syk inhibitor, in rat models of septic and non-septic shock.
Clin Exp Pharmacol Physiol
; 46(2): 173-182, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30347478
2.
The role of Syk/IĸB-α/NF-ĸB pathway activation in the reversal effect of BAY 61-3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan-induced non-septic shock.
Clin Exp Pharmacol Physiol
; 45(2): 155-165, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28949404
3.
Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKß/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock.
Inflamm Res
; 63(9): 741-56, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24915805
4.
Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.
Nitric Oxide
; 33: 18-41, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23684565
5.
NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite.
Prostaglandins Other Lipid Mediat
; 104-105: 93-108, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-22975359
6.
5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKß/IκB-α/NF-κB pathway, and proinflammatory cytokine formation.
Prostaglandins Other Lipid Mediat
; 102-103: 31-41, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23454652
7.
Affirmative effects of iloprost on apoptosis during ischemia-reperfusion injury in kidney as a distant organ.
Ren Fail
; 34(1): 111-8, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22126436
8.
Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats.
Nitric Oxide
; 24(3): 160-72, 2011 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21354320
9.
Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats.
Eur J Pharmacol
; 723: 234-45, 2014 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24296316
10.
Contribution of MEK1/ERK1/2/iNOS pathway to oxidative stress and decreased caspase-3 activity in endotoxemic rats.
Antiinflamm Antiallergy Agents Med Chem
; 11(3): 243-52, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23189948
11.
Increased production of nitric oxide mediates selective organ-specific effects of endotoxin on oxidative stress.
Antiinflamm Antiallergy Agents Med Chem
; 11(2): 161-72, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23173576
12.
A novel treatment strategy for sepsis and septic shock based on the interactions between prostanoids, nitric oxide, and 20-hydroxyeicosatetraenoic acid.
Antiinflamm Antiallergy Agents Med Chem
; 11(2): 121-50, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23013331
13.
Piroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxide.
Basic Clin Pharmacol Toxicol
; 109(3): 186-94, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21463481
14.
Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats.
Basic Clin Pharmacol Toxicol
; 107(5): 877-82, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22545970
15.
A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in rats.
Basic Clin Pharmacol Toxicol
; 106(5): 378-88, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20002062
16.
A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats.
Shock
; 30(3): 329-35, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18323740
17.
Extracellular signal-regulated kinase (ERK1/2) contributes to endotoxin-induced hyporeactivity via nitric oxide and prostacyclin production in rat aorta.
Pharmacology
; 78(3): 123-8, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17008773
18.
Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery.
Cell Biochem Biophys
; 41(3): 331-42, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15509884
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