Detalles de la búsqueda
1.
Process and System Clearances in Pharmacokinetic Models: Our Basic Clearance Concepts Are Correct.
Drug Metab Dispos
; 51(4): 532-542, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36623886
2.
The Rat Continuous Intestine Model Predicts the Impact of Particle Size and Transporters on the Oral Absorption of Glyburide.
Mol Pharm
; 20(1): 219-231, 2023 01 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36541850
3.
Predicting Impact of Food and Feeding Time on Oral Absorption of Drugs with a Novel Rat Continuous Intestinal Absorption Model.
Drug Metab Dispos
; 50(6): 750-761, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35339986
4.
Complex Cytochrome P450 Kinetics Due to Multisubstrate Binding and Sequential Metabolism. Part 1. Theoretical Considerations.
Drug Metab Dispos
; 49(12): 1090-1099, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34503952
5.
Complex Cytochrome P450 Kinetics Due to Multisubstrate Binding and Sequential Metabolism. Part 2. Modeling of Experimental Data.
Drug Metab Dispos
; 49(12): 1100-1108, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34503953
6.
A hybrid model to evaluate the impact of active uptake transport on hepatic distribution of atorvastatin in rats.
Xenobiotica
; 50(5): 536-544, 2020 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-31530243
7.
Numerical analysis of time-dependent inhibition kinetics: comparison between rat liver microsomes and rat hepatocyte data for mechanistic model fitting.
Xenobiotica
; 50(11): 1301-1310, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28644704
8.
Impact of Lipid Partitioning on the Design, Analysis, and Interpretation of Microsomal Time-Dependent Inactivation.
Drug Metab Dispos
; 47(7): 732-742, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31043439
9.
Prediction of Tissue-Plasma Partition Coefficients Using Microsomal Partitioning: Incorporation into Physiologically based Pharmacokinetic Models and Steady-State Volume of Distribution Predictions.
Drug Metab Dispos
; 47(10): 1050-1060, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31324699
10.
Improved Predictions of Drug-Drug Interactions Mediated by Time-Dependent Inhibition of CYP3A.
Mol Pharm
; 15(5): 1979-1995, 2018 05 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29608318
11.
Continuous Intestinal Absorption Model Based on the Convection-Diffusion Equation.
Mol Pharm
; 14(9): 3069-3086, 2017 09 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28712300
12.
Drug Distribution Part 2. Predicting Volume of Distribution from Plasma Protein Binding and Membrane Partitioning.
Pharm Res
; 34(3): 544-551, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27966088
13.
Drug Distribution. Part 1. Models to Predict Membrane Partitioning.
Pharm Res
; 34(3): 535-543, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27981450
14.
On the Nature of Physiologically-Based Pharmacokinetic Models -A Priori or A Posteriori? Mechanistic or Empirical?
Pharm Res
; 34(3): 529-534, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28028770
15.
Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.
Mol Pharm
; 13(8): 2833-43, 2016 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27336918
16.
A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding.
Biopharm Drug Dispos
; 37(3): 123-41, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26531057
17.
A numerical method for analysis of in vitro time-dependent inhibition data. Part 1. Theoretical considerations.
Drug Metab Dispos
; 42(9): 1575-86, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24939654
18.
A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.
Drug Metab Dispos
; 42(9): 1587-95, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24939653
19.
Compartmental models for apical efflux by P-glycoprotein: part 2--a theoretical study on transporter kinetic parameters.
Pharm Res
; 31(2): 335-46, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23959852
20.
Compartmental models for apical efflux by P-glycoprotein--part 1: evaluation of model complexity.
Pharm Res
; 31(2): 347-59, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24019023