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1.
Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney.
Neuro Endocrinol Lett
; 31 Suppl 2: 26-35, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-21187821
2.
Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli.
Protein Expr Purif
; 66(2): 203-9, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19358889
3.
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA.
Neuro Endocrinol Lett
; 29(5): 728-32, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18987592
4.
Cytochromes P450 reconstituted with NADPH: P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes.
Neuro Endocrinol Lett
; 27 Suppl 2: 18-22, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17159771
5.
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy.
Biochem Pharmacol
; 82(6): 669-80, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21683692
6.
Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.
Toxicol Sci
; 121(1): 43-56, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21362632
7.
Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method.
Interdiscip Toxicol
; 2(4): 239-44, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21217860
8.
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2.
Interdiscip Toxicol
; 1(2): 160-8, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21218107
9.
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse.
Toxicol Appl Pharmacol
; 226(3): 318-27, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17976674
10.
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism.
Drug Metab Dispos
; 35(10): 1926-34, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17656468
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