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1.
Conservative Binary Dynamics with a Spinning Black Hole at O(G
Phys Rev Lett
; 130(2): 021601, 2023 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36706419
2.
IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta.
J Exp Med
; 204(4): 747-58, 2007 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-17420268
3.
Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation.
J Immunol
; 187(6): 2853-8, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21841126
4.
Efficacy and Imaging-Enabled Pharmacodynamic Profiling of KRAS G12C Inhibitors in Xenograft and Genetically Engineered Mouse Models of Cancer.
Mol Cancer Ther
; 22(7): 891-900, 2023 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37186518
5.
Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1.
J Med Chem
; 66(7): 4888-4909, 2023 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36940470
6.
Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor.
J Biol Chem
; 286(8): 6433-48, 2011 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-21118801
7.
Design and Characterization of a Pyridone-Containing EZH2 Inhibitor Phosphate Prodrug.
J Med Chem
; 64(3): 1725-1732, 2021 02 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33529029
8.
A B cell receptor with two Igalpha cytoplasmic domains supports development of mature but anergic B cells.
J Exp Med
; 199(6): 855-65, 2004 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15024049
9.
Development of an In Vivo Retrodialysis Calibration Method Using Stable Isotope Labeling to Monitor Metabolic Pathways in the Tumor Microenvironment via Microdialysis.
J Pharm Sci
; 108(9): 3124-3129, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31136767
10.
Basal immunoglobulin signaling actively maintains developmental stage in immature B cells.
PLoS Biol
; 3(3): e82, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15752064
11.
Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation.
Clin Cancer Res
; 24(1): 234-247, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29074603
12.
Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy.
Mol Cancer Ther
; 17(12): 2530-2542, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30232146
13.
Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497).
J Med Chem
; 61(3): 650-665, 2018 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29211475
14.
Identification of sawflies and horntails (Hymenoptera, 'Symphyta') through DNA barcodes: successes and caveats.
Mol Ecol Resour
; 17(4): 670-685, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27768250
15.
Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate.
J Med Chem
; 60(23): 9617-9629, 2017 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29111717
16.
Efficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia vera.
PLoS One
; 7(5): e37207, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22623993
17.
PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
Cancer Res
; 71(8): 3052-65, 2011 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21493594
18.
Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.
Sci Transl Med
; 2(43): 43ra55, 2010 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-20686178
19.
An inhibitor of Janus kinase 2 prevents polycythemia in mice.
Biochem Pharmacol
; 78(4): 382-9, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19413997
20.
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.
Nat Biotechnol
; 27(10): 933-40, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19801977