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1.

Multifunctional NK Cell-Engaging Antibodies Targeting EGFR and NKp30 Elicit Efficient Tumor Cell Killing and Proinflammatory Cytokine Release.

Klausz, Katja; Pekar, Lukas; Boje, Ammelie Svea; Gehlert, Carina Lynn; Krohn, Steffen; Gupta, Tushar; Xiao, Yanping; Krah, Simon; Zaynagetdinov, Rinat; Lipinski, Britta; Toleikis, Lars; Poetzsch, Sven; Rabinovich, Brian; Peipp, Matthias; Zielonka, Stefan.

J Immunol ; 209(9): 1724-1735, 2022 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-36104113

2.

Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement.

Pekar, Lukas; Klausz, Katja; Busch, Michael; Valldorf, Bernhard; Kolmar, Harald; Wesch, Daniela; Oberg, Hans-Heinrich; Krohn, Steffen; Boje, Ammelie Svea; Gehlert, Carina Lynn; Toleikis, Lars; Krah, Simon; Gupta, Tushar; Rabinovich, Brian; Zielonka, Stefan; Peipp, Matthias.

J Immunol ; 206(1): 225-236, 2021 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-33268483

3.

S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma" - update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention.

Leiter, Ulrike; Heppt, Markus V; Steeb, Theresa; Alter, Mareike; Amaral, Teresa; Bauer, Andrea; Bechara, Falk G; Becker, Jürgen C; Breitbart, Eckhard W; Breuninger, Helmut; Diepgen, Thomas; Dirschka, Thomas; Eigentler, Thomas; ElGammal, A K Stephan; Felcht, Moritz; Flaig, Michael J; Follmann, Markus; Fritz, Klaus; Grabbe, Stephan; Greinert, Rüdiger; Gutzmer, Ralf; Hauschild, Axel; Hillen, Uwe; Ihrler, Stephan; John, Swen Malte; Kofler, Lukas; Koelbl, Oliver; Krause-Bergmann, Albrecht; Kraywinkel, Klaus; Krohn, Steffen; Langer, Thomas; Loquai, Carmen; Löser, Christoph R; Mohr, Peter; Nashan, Dorothée; Nothacker, Monika; Pfannenberg, Christina; Salavastru, Carmen; Schmitz, Lutz; Stockfleth, Eggert; Szeimies, Rolf-Markus; Ulrich, Claas; Voelter-Mahlknecht, Susanne; Vordermark, Dirk; Weichenthal, Michael; Welzel, Julia; Wermker, Kai; Wiegand, Susanne; Garbe, Claus; Berking, Carola.

J Dtsch Dermatol Ges ; 21(11): 1422-1433, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37840404

4.

Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy.

Klausz, Katja; Cieker, Michael; Kellner, Christian; Rösner, Thies; Otte, Anna; Krohn, Steffen; Lux, Anja; Nimmerjahn, Falk; Valerius, Thomas; Gramatzki, Martin; Peipp, Matthias.

Haematologica ; 106(7): 1857-1866, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-32499243

5.

S3-Leitlinie "Aktinische Keratose und Plattenepithelkarzinom der Haut" - Update 2023, Teil 1: Therapie der aktinischen Keratose, Morbus Bowen, Cheilitis actinica, berufsbedingte Erkrankung und Versorgungsstrukturen: S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma"- update 2023, part 1: treatment of actinic keratosis, actinic cheilitis, cutaneous squamous cell carcinoma in situ (Bowen's disease), occupational disease and structures of care.

Heppt, Markus V; Leiter, Ulrike; Steeb, Theresa; Alter, Mareike; Amaral, Teresa; Bauer, Andrea; Bechara, Falk G; Becker, Jürgen C; Breitbart, Eckhard W; Breuninger, Helmut; Diepgen, Thomas; Dirschka, Thomas; Eigentler, Thomas; El Gammal, A K Stephan; Felcht, Moritz; Flaig, Michael J; Follmann, Markus; Fritz, Klaus; Grabbe, Stephan; Greinert, Rüdiger; Gutzmer, Ralf; Hauschild, Axel; Hillen, Uwe; Ihrler, Stephan; John, Swen Malte; Kofler, Lukas; Koelbl, Oliver; Krause-Bergmann, Albrecht; Kraywinkel, Klaus; Krohn, Steffen; Langer, Thomas; Loquai, Carmen; Löser, Christoph R; Mohr, Peter; Nashan, Dorothée; Nothacker, Monika; Pfannenberg, Christina; Salavastru, Carmen; Schmitz, Lutz; Stockfleth, Eggert; Szeimies, Rolf-Markus; Ulrich, Claas; Voelter-Mahlknecht, Susanne; Vordermark, Dirk; Weichenthal, Michael; Welzel, Julia; Wermker, Kai; Wiegand, Susanne; Garbe, Claus; Berking, Carola.

J Dtsch Dermatol Ges ; 21(10): 1249-1262, 2023 10.

Artículo en Alemán | MEDLINE | ID: mdl-37845050

6.

S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma"- update 2023, part 1: treatment of actinic keratosis, actinic cheilitis, cutaneous squamous cell carcinoma in situ (Bowen's disease), occupational disease and structures of care.

Heppt, Markus V; Leiter, Ulrike; Steeb, Theresa; Alter, Mareike; Amaral, Teresa; Bauer, Andrea; Bechara, Falk G; Becker, Jürgen C; Breitbart, Eckhard W; Breuninger, Helmut; Diepgen, Thomas; Dirschka, Thomas; Eigentler, Thomas; El Gammal, A K Stephan; Felcht, Moritz; Flaig, Michael J; Follmann, Markus; Fritz, Klaus; Grabbe, Stephan; Greinert, Rüdiger; Gutzmer, Ralf; Hauschild, Axel; Hillen, Uwe; Ihrler, Stephan; John, Swen Malte; Kofler, Lukas; Koelbl, Oliver; Krause-Bergmann, Albrecht; Kraywinkel, Klaus; Krohn, Steffen; Langer, Thomas; Loquai, Carmen; Löser, Christoph R; Mohr, Peter; Nashan, Dorothée; Nothacker, Monika; Pfannenberg, Christina; Salavastru, Carmen; Schmitz, Lutz; Stockfleth, Eggert; Szeimies, Rolf-Markus; Ulrich, Claas; Voelter-Mahlknecht, Susanne; Vordermark, Dirk; Weichenthal, Michael; Welzel, Julia; Wermker, Kai; Wiegand, Susanne; Garbe, Claus; Berking, Carola.

J Dtsch Dermatol Ges ; 21(10): 1249-1262, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37845077

7.

S3-Leitlinie "Aktinische Keratose und Plattenepithelkarzinom der Haut" - Update 2023, Teil 2: Epidemiologie und Ätiologie, Diagnostik, Therapie des invasiven Plattenepithelkarzinoms der Haut, Nachsorge und Prävention: S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma" - update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention.

Leiter, Ulrike; Heppt, Markus V; Steeb, Theresa; Alter, Mareike; Amaral, Teresa; Bauer, Andrea; Bechara, Falk G; Becker, Jürgen C; Breitbart, Eckhard W; Breuninger, Helmut; Diepgen, Thomas; Dirschka, Thomas; Eigentler, Thomas; El Gammal, A K Stephan; Felcht, Moritz; Flaig, Michael J; Follmann, Markus; Fritz, Klaus; Grabbe, Stephan; Greinert, Rüdiger; Gutzmer, Ralf; Hauschild, Axel; Hillen, Uwe; Ihrler, Stephan; John, Swen Malte; Kofler, Lukas; Koelbl, Oliver; Krause-Bergmann, Albrecht; Kraywinkel, Klaus; Krohn, Steffen; Langer, Thomas; Loquai, Carmen; Löser, Christoph R; Mohr, Peter; Nashan, Dorothée; Nothacker, Monika; Pfannenberg, Christina; Salavastru, Carmen; Schmitz, Lutz; Stockfleth, Eggert; Szeimies, Rolf-Markus; Ulrich, Claas; Voelter-Mahlknecht, Susanne; Vordermark, Dirk; Weichenthal, Michael; Welzel, Julia; Wermker, Kai; Wiegand, Susanne; Garbe, Claus; Berking, Carola.

J Dtsch Dermatol Ges ; 21(11): 1422-1434, 2023 11.

Artículo en Alemán | MEDLINE | ID: mdl-37946644

8.

Skin cancer induced by natural UV-radiation as an occupational diseaserequirements for its notification and recognition.

Diepgen, Thomas L; Brandenburg, Stephan; Aberer, Werner; Bauer, Andrea; Drexler, Hans; Fartasch, Manigé; John, Swen Malte; Krohn, Steffen; Palfner, Stefanie; Römer, Wolfgang; Schuhmacher-Stock, Uta; Elsner, Peter.

J Dtsch Dermatol Ges ; 12(12): 1102-6, 2014 Dec.

Artículo en Inglés, Alemán | MEDLINE | ID: mdl-25482691

9.

Psoriasis predisposition and occupational triggering factors in the appraisal of occupational medical expertises.

Mahler, Vera; Diepgen, Thomas; Skudlik, Christoph; Becker, Detlef; Dickel, Heinrich; Fartasch, Manige; Geier, Johannes; Häberle, Michael; Hillen, Uwe; Krohn, Steffen; John, Swen Malte; Weisshaar, Elke; Werfel, Thomas; Zagrodnik, Fred.

J Dtsch Dermatol Ges ; 12(6): 519-29, 2014 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-24889306

10.

Combining Cellular Immunization and Phage Display Screening Results in Novel, FcÎ³RI-Specific Antibodies.

Krohn, Steffen; Holtrop, Tosca; Brandsma, Arianne M; Moerer, Petra; Nederend, Maaike; Darzentas, Nikos; Brüggemann, Monika; Klausz, Katja; Leusen, Jeanette H W; Peipp, Matthias.

Viruses ; 16(4)2024 04 12.

Artículo en Inglés | MEDLINE | ID: mdl-38675937

11.

Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers.

Boje, Ammelie Svea; Pekar, Lukas; Koep, Katharina; Lipinski, Britta; Rabinovich, Brian; Evers, Andreas; Gehlert, Carina Lynn; Krohn, Steffen; Xiao, Yanping; Krah, Simon; Zaynagetdinov, Rinat; Toleikis, Lars; Poetzsch, Sven; Peipp, Matthias; Zielonka, Stefan; Klausz, Katja.

MAbs ; 16(1): 2315640, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38372053

12.

Identification of New Antibodies Targeting Tumor Cell Surface Antigens by Phage Display.

Krohn, Steffen; Peipp, Matthias; Klausz, Katja.

Methods Mol Biol ; 2681: 61-82, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37405643

13.

Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells.

Lutz, Sebastian; Klausz, Katja; Albici, Anca-Maria; Ebinger, Lea; Sellmer, Lea; Teipel, Hannah; Frenzel, André; Langner, Anna; Winterberg, Dorothee; Krohn, Steffen; Hust, Michael; Schirrmann, Thomas; Dübel, Stefan; Scherließ, Regina; Humpe, Andreas; Gramatzki, Martin; Kellner, Christian; Peipp, Matthias.

Front Immunol ; 14: 1227572, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37965326

14.

Identification of New Antibodies Targeting Malignant Plasma Cells for Immunotherapy by Next-Generation Sequencing-Assisted Phage Display.

Krohn, Steffen; Boje, Ammelie Svea; Gehlert, Carina Lynn; Lutz, Sebastian; Darzentas, Nikos; Knecht, Henrik; Herrmann, Dietrich; Brüggemann, Monika; Scheidig, Axel J; Weisel, Katja; Gramatzki, Martin; Peipp, Matthias; Klausz, Katja.

Front Immunol ; 13: 908093, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35784366

15.

The Novel Dual Topoisomerase Inhibitor P8-D6 Shows Anti-myeloma Activity In Vitro and In Vivo.

Klausz, Katja; Kellner, Christian; Gehlert, Carina Lynn; Krohn, Steffen; Wilcken, Hauke; Floerkemeier, Inken; Günther, Andreas; Bauerschlag, Dirk O; Clement, Bernd; Gramatzki, Martin; Peipp, Matthias.

Mol Cancer Ther ; 21(1): 70-78, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34725192

16.

Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody.

Gehlert, Carina Lynn; Rahmati, Pegah; Boje, Ammelie Svea; Winterberg, Dorothee; Krohn, Steffen; Theocharis, Thomas; Cappuzzello, Elisa; Lux, Anja; Nimmerjahn, Falk; Ludwig, Ralf J; Lustig, Marta; Rösner, Thies; Valerius, Thomas; Schewe, Denis Martin; Kellner, Christian; Klausz, Katja; Peipp, Matthias.

Front Immunol ; 13: 957874, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36119088

17.

Psoriasis predisposition and occupational triggering factors in the appraisal of occupational medical expertises.

Mahler, Vera; Diepgen, Thomas; Skudlik, Christoph; Becker, Detlef; Dickel, Heinrich; Fartasch, Manige; Geier, Johannes; Häberle, Michael; Hillen, Uwe; Krohn, Steffen; John, Swen Malte; Weisshaar, Elke; Werfel, Thomas; Zagrodnik, Fred.

J Dtsch Dermatol Ges ; 12(6): e1-4, 2014 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-24889310

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Multifunctional NK Cell-Engaging Antibodies Targeting EGFR and NKp30 Elicit Efficient Tumor Cell Killing and Proinflammatory Cytokine Release.

Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement.

S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma" - update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention.

Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy.

S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma"- update 2023, part 1: treatment of actinic keratosis, actinic cheilitis, cutaneous squamous cell carcinoma in situ (Bowen's disease), occupational disease and structures of care.

Skin cancer induced by natural UV-radiation as an occupational diseaserequirements for its notification and recognition.

Psoriasis predisposition and occupational triggering factors in the appraisal of occupational medical expertises.

Combining Cellular Immunization and Phage Display Screening Results in Novel, FcÎ³RI-Specific Antibodies.

Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers.

Identification of New Antibodies Targeting Tumor Cell Surface Antigens by Phage Display.

Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells.

Identification of New Antibodies Targeting Malignant Plasma Cells for Immunotherapy by Next-Generation Sequencing-Assisted Phage Display.

The Novel Dual Topoisomerase Inhibitor P8-D6 Shows Anti-myeloma Activity In Vitro and In Vivo.

Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody.

Psoriasis predisposition and occupational triggering factors in the appraisal of occupational medical expertises.