Detalles de la búsqueda
1.
Auer Rods.
N Engl J Med
; 376(21): 2065, 2017 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-28538120
2.
Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737.
Mol Cancer Ther
; 8(4): 883-92, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19372561
3.
Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt.
Lung Cancer
; 60(2): 166-74, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18006183
4.
Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression.
Clin Cancer Res
; 24(2): 360-369, 2018 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29118061
5.
Imatinib inhibits c-Kit-induced hypoxia-inducible factor-1alpha activity and vascular endothelial growth factor expression in small cell lung cancer cells.
Mol Cancer Ther
; 5(6): 1415-22, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16818499
6.
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy.
Clin Cancer Res
; 11(4): 1563-71, 2005 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15746061
7.
The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
Cancer Res
; 63(8): 1822-33, 2003 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12702569
8.
Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
Cancer Res
; 62(1): 188-99, 2002 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11782377
9.
Histone deacetylase inhibitors promote STI571-mediated apoptosis in STI571-sensitive and -resistant Bcr/Abl+ human myeloid leukemia cells.
Cancer Res
; 63(9): 2118-26, 2003 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12727828
10.
Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer.
Cancer Biol Ther
; 17(1): 27-35, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26575826
11.
Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes.
Biochem Pharmacol
; 70(11): 1685-96, 2005 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-16207485
12.
Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells.
Clin Cancer Res
; 8(9): 2976-84, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12231544
13.
Flavopiridol potently induces small cell lung cancer apoptosis during S phase in a manner that involves early mitochondrial dysfunction.
Clin Cancer Res
; 9(12): 4586-94, 2003 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14555534
14.
Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy.
Mol Cancer Ther
; 1(11): 913-22, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12481412
15.
The insulin-like growth factor-I (IGF-I) receptor kinase inhibitor NVP-ADW742, in combination with STI571, delineates a spectrum of dependence of small cell lung cancer on IGF-I and stem cell factor signaling.
Mol Cancer Ther
; 3(5): 527-35, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15141010
16.
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.
Oncotarget
; 6(17): 15332-47, 2015 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25895029
17.
Induction of apoptosis in BCR/ABL+ cells by histone deacetylase inhibitors involves reciprocal effects on the RAF/MEK/ERK and JNK pathways.
Cancer Biol Ther
; 2(5): 544-51, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14614324
18.
Overview of rationale and clinical trials with signal transduction inhibitors in lung cancer.
Semin Oncol
; 29(1 Suppl 4): 15-26, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-11894010
19.
Imatinib mesylate (STI571) for myeloid malignancies other than CML.
Leuk Res
; 28 Suppl 1: S53-9, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15036942
20.
The multi-targeted kinase inhibitor SU5416 inhibits small cell lung cancer growth and angiogenesis, in part by blocking Kit-mediated VEGF expression.
Lung Cancer
; 46(3): 283-91, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15541812