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1.
Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys.
PLoS Biol
; 22(1): e3002445, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38163325
2.
A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network.
Acta Pharmacol Sin
; 43(11): 3002-3010, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-35513432
3.
Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators.
Acta Pharmacol Sin
; 42(3): 491-498, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-32661351
4.
3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and preliminary evaluation for PET imaging of metabotropic glutamate receptor subtype 2.
Bioorg Med Chem Lett
; 30(23): 127555, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32941990
5.
Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging.
Bioorg Med Chem Lett
; 30(16): 127326, 2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32631531
6.
Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging γ-8 dependent transmembrane AMPA receptor regulatory protein by PET.
Bioorg Med Chem Lett
; 30(4): 126879, 2020 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31879207
7.
Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate.
Bioorg Med Chem
; 27(16): 3568-3573, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31278005
8.
Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain.
Bioorg Med Chem
; 27(3): 483-491, 2019 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30611634
9.
Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain.
Org Biomol Chem
; 16(37): 8325-8335, 2018 09 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30206613
10.
[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18â¯kDa).
Bioorg Med Chem
; 26(17): 4817-4822, 2018 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30166255
11.
Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies.
Brain
; 140(3): 764-780, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28087578
12.
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
J Neurosci
; 36(2): 375-84, 2016 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-26758830
13.
Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors.
J Neurosci
; 36(45): 11544-11558, 2016 11 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27911758
14.
[11C]BCTC: Radiosynthesis and in vivo binding to transient receptor potential vanilloid subfamily member 1 (TRPV1) receptor in the mouse trigeminal nerve.
Bioorg Med Chem Lett
; 27(19): 4521-4524, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28888821
15.
Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain.
Bioorg Med Chem Lett
; 27(14): 3139-3143, 2017 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28571823
16.
Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[11C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([11C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain.
Bioorg Med Chem
; 25(3): 1014-1021, 2017 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28049619
17.
Radiosynthesis and evaluation of 5-methyl-N-(4-[(11)C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([(11)C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4).
Bioorg Med Chem Lett
; 26(2): 370-374, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26707390
18.
N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[(11)C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase.
Bioorg Med Chem
; 24(4): 627-34, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26740152
19.
Radiosynthesis and preliminary PET evaluation of glycogen synthase kinase 3ß (GSK-3ß) inhibitors containing [(11)C]methylsulfanyl, [(11)C]methylsulfinyl or [(11)C]methylsulfonyl groups.
Bioorg Med Chem Lett
; 25(16): 3230-3, 2015 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26067173
20.
Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker α5ß1 Integrin.
Biol Pharm Bull
; 38(11): 1722-31, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26277991