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1.
Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation.
J Biol Chem
; 289(21): 14534-46, 2014 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24711457
2.
Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.
J Biol Chem
; 288(18): 12753-65, 2013 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-23493397
3.
A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization.
Exp Eye Res
; 129: 18-23, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25305577
4.
Prolonged SRC kinase activation, a mechanism to turn transient, sublytic complement activation into a sustained pathological condition in retinal pigment epithelium cells.
Adv Exp Med Biol
; 801: 221-7, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24664702
5.
Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers.
J Biol Chem
; 286(27): 23717-24, 2011 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-21566137
6.
Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury.
J Biol Chem
; 284(25): 16939-16947, 2009 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-19386604
7.
Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice.
Mol Vis
; 16: 1004-18, 2010 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-20577653
8.
Aseptic injury to epithelial cells alters cell surface complement regulation in a tissue specific fashion.
Adv Exp Med Biol
; 664: 151-8, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20238013
9.
A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Adv Exp Med Biol
; 703: 137-49, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20711712
10.
Paradoxical role of BDNF: BDNF+/- retinas are protected against light damage-mediated stress.
Invest Ophthalmol Vis Sci
; 48(6): 2877-86, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17525224
11.
Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage.
Invest Ophthalmol Vis Sci
; 48(11): 5282-9, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17962484
12.
Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells.
Adv Exp Med Biol
; 723: 23-30, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22183311
13.
Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells.
Sci Rep
; 6: 23794, 2016 Mar 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-27029558
14.
Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization.
Invest Ophthalmol Vis Sci
; 56(3): 1850-63, 2015 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25593023
15.
Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium.
Invest Ophthalmol Vis Sci
; 56(8): 4231-8, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26161984
16.
Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury.
PLoS One
; 8(6): e67894, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23825688
17.
Differential effects of rapamycin on rods and cones during light-induced stress in albino mice.
Invest Ophthalmol Vis Sci
; 52(6): 2967-75, 2011 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21273550
18.
The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization.
Mol Immunol
; 48(6-7): e1-8, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21257205
19.
Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement.
Invest Ophthalmol Vis Sci
; 50(10): 4858-64, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19407011
20.
A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
Invest Ophthalmol Vis Sci
; 50(7): 3056-64, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19264882