Detalles de la búsqueda
1.
Anti-Inflammatory Effects of a Novel Nuclear Factor-κB Inhibitory Derivative Derived from Pyrazolo[3,4-d]Pyrimidine in Three Inflammation Models.
J Pharmacol Exp Ther
; 388(3): 788-797, 2024 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38253385
2.
Effect of N-o-nitrobenzylation on conformation and membrane permeability of linear peptides.
Bioorg Chem
; 145: 107220, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38387401
3.
Quantitative Model Analysis and Simulation of Pharmacokinetics and Metastasis-Associated Lung Adenocarcinoma 1 RNA Knockdown Effect After Systemic Administration of Cholesterol-Conjugated DNA/RNA Heteroduplex Oligonucleotide Crossing Blood-Brain Barrier of Mice.
J Pharmacol Exp Ther
; 384(1): 197-204, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36273821
4.
Progress in the Quantitative Assessment of Transporter-Mediated Drug-Drug Interactions Using Endogenous Substrates in Clinical Studies.
Drug Metab Dispos
; 51(9): 1105-1113, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37169512
5.
Impact of Direction of Transport on the Evaluation of Substrate Recognition of Mouse Multidrug and Toxin Extrusion Protein 1.
Drug Metab Dispos
; 51(5): 583-590, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36669855
6.
NRBdMF: A Recommendation Algorithm for Predicting Drug Effects Considering Directionality.
J Chem Inf Model
; 63(2): 474-483, 2023 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36635231
7.
Usefulness of Human Jejunal Spheroid-Derived Differentiated Intestinal Epithelial Cells for the Prediction of Intestinal Drug Absorption in Humans.
Drug Metab Dispos
; 50(3): 204-213, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34992074
8.
A rapid and simple electrochemical detection of the free drug concentration in human serum using boron-doped diamond electrodes.
Analyst
; 147(20): 4442-4449, 2022 Oct 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36129310
9.
Investigation of a Data Split Strategy Involving the Time Axis in Adverse Event Prediction Using Machine Learning.
J Chem Inf Model
; 62(17): 3982-3992, 2022 09 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35971760
10.
Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood-brain barrier.
J Pharmacol Sci
; 148(1): 142-151, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34924119
11.
Frequency of null genotypes of glutathione S-transferase M1 and T1 in Japanese patients with drug-induced liver injury.
Hepatol Res
; 52(10): 882-887, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35834381
12.
A randomized trial to examine the impact of food on pharmacokinetics of 4-phenylbutyrate and change in amino acid availability after a single oral administration of sodium 4-phenylbutyrarte in healthy volunteers.
Mol Genet Metab
; 132(4): 220-226, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33648834
13.
Impact of Direction of Transport on the Evaluation of Inhibition Potencies of Multidrug and Toxin Extrusion Protein 1 Inhibitors.
Drug Metab Dispos
; 49(2): 152-158, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33262224
14.
Characterization of the Human Intestinal Drug Transport with Ussing Chamber System Incorporating Freshly Isolated Human Jejunum.
Drug Metab Dispos
; 49(1): 84-93, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33087448
15.
Functional Investigation of Solute Carrier Family 35, Member F2, in Three Cellular Models of the Primate Blood-Brain Barrier.
Drug Metab Dispos
; 49(1): 3-11, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33144341
16.
Multi-omics analysis of hiPSCs-derived HLCs matured on-chip revealed patterns typical of liver regeneration.
Biotechnol Bioeng
; 118(10): 3716-3732, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33404112
17.
Decomposition Profile Data Analysis for Deep Understanding of Multiple Effects of Natural Products.
J Nat Prod
; 84(4): 1283-1293, 2021 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33836128
18.
Analysis of hiPSCs differentiation toward hepatocyte-like cells upon extended exposition to oncostatin.
Differentiation
; 114: 36-48, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32563741
19.
Impact of P-Glycoprotein-Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates.
Drug Metab Dispos
; 48(11): 1183-1190, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32862147
20.
Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel.
Drug Metab Dispos
; 48(5): 387-394, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32114508