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1.
Elucidation of the mechanism of N-demethylation catalyzed by cytochrome P450 monooxygenase is facilitated by exploiting nitrogen-15 heavy isotope effects.
Arch Biochem Biophys
; 510(1): 35-41, 2011 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21420927
2.
Probing stereoselectivity and pro-chirality of hydride transfer during short-chain alcohol dehydrogenase activity: a combined quantitative 2H NMR and computational approach.
Arch Biochem Biophys
; 482(1-2): 42-51, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19061855
3.
Quantitative isotopic 13C nuclear magnetic resonance at natural abundance to probe enzyme reaction mechanisms via site-specific isotope fractionation: the case of the chain-shortening reaction for the bioconversion of ferulic acid to vanillin.
Anal Biochem
; 393(2): 182-8, 2009 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19563771
4.
Determination of nitrogen-15 isotope fractionation in tropine: evaluation of extraction protocols for isotope ratio measurement by isotope ratio mass spectrometry.
Rapid Commun Mass Spectrom
; 23(24): 4031-7, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19924779
5.
Validation of semiempirical methods for modeling of corrinoid systems.
J Inorg Biochem
; 98(6): 1078-86, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15149818
6.
Cytochrome P450-catalyzed degradation of nicotine: fundamental parameters determining hydroxylation by cytochrome P450 2A6 at the 5'-carbon or the n-methyl carbon.
J Phys Chem B
; 116(27): 7827-40, 2012 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22676413
7.
Investigation of the mechanism of nicotine demethylation in Nicotiana through 2H and 15N heavy isotope effects: implication of cytochrome P450 oxidase and hydroxyl ion transfer.
Arch Biochem Biophys
; 458(2): 175-83, 2007 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17254540
8.
Computational insights into the mechanism of radical generation in B12-dependent methylmalonyl-CoA mutase.
J Am Chem Soc
; 128(4): 1287-92, 2006 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16433547
9.
Synthesis, cytotoxic effect, and structure-activity relationship of Pd(II) complexes with coumarin derivatives.
Inorg Chem
; 45(24): 9688-95, 2006 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-17112264
10.
Mechanism of the reaction catalyzed by DL-2-haloacid dehalogenase as determined from kinetic isotope effects.
Biochemistry
; 45(19): 6012-7, 2006 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-16681373
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