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1.
The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-ß-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
Bioorg Med Chem Lett
; 27(18): 4323-4330, 2017 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28835346
2.
Synthesis of 2'-O,4'-C-alkylene-bridged ribonucleosides and their evaluation as inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 24(12): 2699-702, 2014 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24815510
3.
Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
J Med Chem
; 48(11): 3858-73, 2005 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-15916438
4.
Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations.
J Med Chem
; 47(15): 3892-6, 2004 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15239667
5.
Synthesis and antiproliferative activity of 3-aryl-2-(1H-benzotriazol-1-yl)acrylonitriles. Part III.
Eur J Med Chem
; 37(11): 891-900, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12446048
6.
Anti-HIV-1 activity of pyrryl aryl sulfone (PAS) derivatives: synthesis and SAR studies of novel esters and amides at the position 2 of the pyrrole nucleus.
Farmaco
; 59(3): 201-10, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-14987983
7.
2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays.
Bioorg Med Chem
; 12(1): 199-215, 2004 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-14697785
8.
6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays.
Bioorg Med Chem Lett
; 14(7): 1745-9, 2004 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-15026063
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