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1.
DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target.
Bioorg Chem
; 115: 105231, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34388485
2.
Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Nucleic Acids Res
; 45(14): 8378-8391, 2017 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-28637278
3.
A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late-stage Trypanosoma brucei brucei infection is not cross-resistant with diamidines.
Antimicrob Agents Chemother
; 59(2): 890-904, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25421467
4.
Lactose binding to human galectin-7 (p53-induced gene 1) induces long-range effects through the protein resulting in increased dimer stability and evidence for positive cooperativity.
Glycobiology
; 23(5): 508-23, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23376190
5.
Fine-tuning of prototype chicken galectins: structure of CG-2 and structure-activity correlations.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 9): 1665-76, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23999290
6.
Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.
J Med Chem
; 66(19): 13452-13480, 2023 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37729094
7.
Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK-eNOS-NO pathway.
Sci Rep
; 12(1): 4225, 2022 03 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35273216
8.
Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease.
ACS Chem Neurosci
; 13(2): 275-287, 2022 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34962383
9.
Deciphering Structural Determinants in Chondroitin Sulfate Binding to FGF-2: Paving the Way to Enhanced Predictability of their Biological Functions.
Polymers (Basel)
; 13(2)2021 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33478164
10.
Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency.
Pharmaceutics
; 13(11)2021 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34834203
11.
The structure and flexibility analysis of the Arabidopsis synaptotagmin 1 reveal the basis of its regulation at membrane contact sites.
Life Sci Alliance
; 4(10)2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34408000
12.
Insights into pneumococcal pathogenesis from the crystal structure of the modular teichoic acid phosphorylcholine esterase Pce.
Nat Struct Mol Biol
; 12(6): 533-8, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15895092
13.
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Eur J Med Chem
; 190: 112090, 2020 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32018096
14.
Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington's disease treatment.
Sci Rep
; 9(1): 7260, 2019 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31086218
15.
Identification of IQM-266, a Novel DREAM Ligand That Modulates KV4 Currents.
Front Mol Neurosci
; 12: 11, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30787866
16.
Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics.
Chem Commun (Camb)
; 54(95): 13455-13458, 2018 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30431033
17.
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4.
ACS Cent Sci
; 4(9): 1274-1290, 2018 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30276263
18.
Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis.
J Med Chem
; 59(14): 6753-6771, 2016 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-27309150
19.
Pneumococcal phosphorylcholine esterase, Pce, contains a metal binuclear center that is essential for substrate binding and catalysis.
Protein Sci
; 14(12): 3013-24, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16260756
20.
Crystallization and preliminary X-ray diffraction studies of the pneumococcal teichoic acid phosphorylcholine esterase Pce.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 2): 221-4, 2005 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16511000