Detalles de la búsqueda
1.
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis.
Mol Pharm
; 21(2): 864-872, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38134445
2.
Synthesis and in vitro cytotoxicity of benzoxazole-based PPARα/γ antagonists in colorectal cancer cell lines.
Arch Pharm (Weinheim)
; : e2400086, 2024 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38807029
3.
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE).
Molecules
; 27(3)2022 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-35164223
4.
Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors.
Bioorg Med Chem
; 28(3): 115257, 2020 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31874775
5.
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors.
Int J Mol Sci
; 21(19)2020 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32987725
6.
Synthesis of novel benzothiazole amides: Evaluation of PPAR activity and anti-proliferative effects in paraganglioma, pancreatic and colorectal cancer cell lines.
Bioorg Med Chem Lett
; 29(16): 2302-2306, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31272790
7.
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease.
Molecules
; 23(9)2018 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-30158491
8.
Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids.
J Enzyme Inhib Med Chem
; 32(1): 1260-1264, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28948845
9.
Single-Nucleotide Polymorphism of PPARγ, a Protein at the Crossroads of Physiological and Pathological Processes.
Int J Mol Sci
; 18(2)2017 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28208577
10.
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin.
Toxicol Appl Pharmacol
; 306: 36-46, 2016 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27377005
11.
An Effective Virtual Screening Protocol To Identify Promising p53-MDM2 Inhibitors.
J Chem Inf Model
; 56(6): 1216-27, 2016 06 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27269808
12.
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity.
J Enzyme Inhib Med Chem
; 31(sup4): 25-37, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27556138
13.
Seeking for Non-Zinc-Binding MMP-2 Inhibitors: Synthesis, Biological Evaluation and Molecular Modelling Studies.
Int J Mol Sci
; 17(10)2016 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27782083
14.
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency.
Plant Foods Hum Nutr
; 71(1): 81-7, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26852311
15.
LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.
J Biol Chem
; 289(10): 6908-6920, 2014 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24451380
16.
Structural basis of the transactivation deficiency of the human PPARγ F360L mutant associated with familial partial lipodystrophy.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 7): 1965-76, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25004973
17.
A chemical modification of a peroxisome proliferator-activated receptor pan agonist produced a shift to a new dual alpha/gamma partial agonist endowed with mitochondrial pyruvate carrier inhibition and antidiabetic properties.
Eur J Med Chem
; 275: 116567, 2024 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38865743
18.
Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors.
Bioorg Med Chem
; 21(21): 6456-65, 2013 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24071448
19.
Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition.
Biomolecules
; 13(4)2023 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37189440
20.
Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases.
Dalton Trans
; 52(18): 6117-6128, 2023 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37066998