Detalles de la búsqueda
1.
IDO1 Inhibition Promotes Activation of Tumor-intrinsic STAT3 Pathway and Induces Adverse Tumor-protective Effects.
J Immunol
; 212(7): 1232-1243, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38391297
2.
Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy.
J Immunol
; 209(1): 180-191, 2022 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35725271
3.
Correction: Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy.
J Immunol
; 211(1): 163, 2023 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37195178
4.
Discovery of secondary sulphonamides as IDO1 inhibitors with potent antitumour effects in vivo.
J Enzyme Inhib Med Chem
; 35(1): 1240-1257, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32466694
5.
Copper-Catalyzed Diaryl Ether Formation from (Hetero)aryl Halides at Low Catalytic Loadings.
J Org Chem
; 82(9): 4964-4969, 2017 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28427259
6.
Structure-based discovery of novel 4,5,6-trisubstituted pyrimidines as potent covalent Bruton's tyrosine kinase inhibitors.
Bioorg Med Chem Lett
; 26(13): 3052-3059, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27210433
7.
Synthesis of naked amino-pyrroloindoline via direct aminocyclization of tryptamine.
Org Biomol Chem
; 13(19): 5381-4, 2015 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25881571
8.
Effective virtual screening strategy toward covalent ligands: identification of novel NEDD8-activating enzyme inhibitors.
J Chem Inf Model
; 54(6): 1785-97, 2014 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24857708
9.
Targeting MutT Homolog 1 (MTH1) for Breast Cancer Suppression by Using a Novel MTH1 Inhibitor MA-24 with Tumor-Selective Toxicity.
Pharmaceuticals (Basel)
; 17(3)2024 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38543077
10.
Highly enantioselective bromocyclization of tryptamines and its application in the synthesis of (-)-chimonanthine.
Angew Chem Int Ed Engl
; 52(49): 12924-7, 2013 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-24123660
11.
Structure-Based Drug Design of Novel Triaminotriazine Derivatives as Orally Bioavailable IDH2R140Q Inhibitors with High Selectivity and Reduced hERG Inhibitory Activity for the Treatment of Acute Myeloid Leukemia.
J Med Chem
; 66(18): 12894-12910, 2023 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37706660
12.
Ethylene glycol-linked amino acid diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability and pharmacokinetics.
Mol Pharm
; 9(8): 2127-35, 2012 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22352697
13.
Synthesis of symmetrical and unsymmetrical N,N'-diaryl guanidines via copper/N-methylglycine-catalyzed arylation of guanidine nitrate.
J Org Chem
; 77(12): 5449-53, 2012 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22655905
14.
Synthesis and evaluation of nitric oxide-releasing DDB derivatives as potential Pgp-mediated MDR reversal agents in MCF-7/Adr cells.
Bioorg Med Chem Lett
; 22(2): 801-5, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22209486
15.
Synthesis and evaluation of substituted dibenzo[c,e]azepine-5-ones as P-glycoprotein-mediated multidrug resistance reversal agents.
Bioorg Med Chem Lett
; 22(8): 2675-80, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22450134
16.
Studies on the enantiomers of ZJM-289: synthesis and biological evaluation of antiplatelet, antithrombotic and neuroprotective activities.
Org Biomol Chem
; 10(45): 9030-40, 2012 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23076046
17.
Glycosylated diazeniumdiolate-based oleanolic acid derivatives: synthesis, in vitro and in vivo biological evaluation as anti-human hepatocellular carcinoma agents.
Org Biomol Chem
; 10(19): 3882-91, 2012 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22473516
18.
Synthesis and biological evaluation of bifendate-chalcone hybrids as a new class of potential P-glycoprotein inhibitors.
Bioorg Med Chem
; 20(8): 2540-8, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22429509
19.
Pharmacokinetic, distribution, metabolism, and excretion of (Z)-2-amino-1,5-dihydro-1-methyl-5-[4-(mesyl)benzylidene]-4H-imidazol-4-one mesilate (ZLJ-601) in Sprague-Dawley rats.
Pharmacology
; 89(3-4): 192-200, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22456195
20.
Ultrafast chiral peptides purification via surface plasmon enhanced spin selectivity.
Biosens Bioelectron
; 211: 114339, 2022 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35588636