Detalles de la búsqueda
1.
Changes in the brain transcriptome after DNA Aß42 trimer immunization in a 3xTg-AD mouse model.
Neurobiol Dis
; 148: 105221, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33316368
2.
DNA Aß42 immunization via needle-less Jet injection in mice and rabbits as potential immunotherapy for Alzheimer's disease.
J Neurol Sci
; 446: 120564, 2023 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36731358
3.
Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aß immunotherapy.
Aging Brain
; 3: 100066, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36911262
4.
CSF-Derived CD4+ T-Cell Diversity Is Reduced in Patients With Alzheimer Clinical Syndrome.
Neurol Neuroimmunol Neuroinflamm
; 9(1)2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34848502
5.
Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet.
J Neuroinflammation
; 8: 73, 2011 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-21702922
6.
DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation.
Cell Mol Neurobiol
; 31(6): 867-74, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21625960
7.
DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.
JAMA
; 302(16): 1796-802, 2009 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-19861672
8.
Active full-length DNA Aß42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology.
Alzheimers Res Ther
; 10(1): 115, 2018 11 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30454039
9.
Intradermal active full-length DNA Aß42 immunization via electroporation leads to high anti-Aß antibody levels in wild-type mice.
J Neuroimmunol
; 322: 15-25, 2018 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29958693
10.
Cerebrospinal fluid B cells from multiple sclerosis patients are subject to normal germinal center selection.
J Neuroimmunol
; 183(1-2): 189-99, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17169437
11.
Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MS.
J Neuroimmunol
; 186(1-2): 164-76, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17451814
12.
Evaluation of a DNA Aß42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aß42 trimer.
Alzheimers Res Ther
; 9(1): 30, 2017 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-28441965
13.
Evaluation of a DNA Aß42 Vaccine in Aged NZW Rabbits: Antibody Kinetics and Immune Profile after Intradermal Immunization with Full-Length DNA Aß42 Trimer.
J Alzheimers Dis
; 57(1): 97-112, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28222511
14.
Laquinimod has no effects on brain volume or cellular CNS composition in the F1 3xTg-AD/C3H mouse model of Alzheimer's disease.
J Neuroimmunol
; 309: 100-110, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28601278
15.
Genomics of Alzheimer Disease: A Review.
JAMA Neurol
; 73(7): 867-74, 2016 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27135718
16.
A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR.
PLoS One
; 11(4): e0152720, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27054574
17.
Active Immunotherapy to Prevent Alzheimer Disease-A DNA Amyloid ß 1-42 Trimer Vaccine.
JAMA Neurol
; 77(3): 289-290, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31816028
18.
Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4+CD25+Foxp3+ T cells (Tregs) in a mouse study for active DNA Aß42 immunotherapy.
J Neuroimmunol
; 278: 90-9, 2015 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25595257
19.
A noninflammatory immune response in aged DNA Aß42-immunized mice supports its safety for possible use as immunotherapy in AD patients.
Neurobiol Aging
; 36(3): 1274-81, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25725942
20.
Advances in the development of vaccines for Alzheimer's disease.
Discov Med
; 15(84): 319-26, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23725605