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1.
Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability.
Chemistry
; 26(65): 15035-15044, 2020 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32633095
2.
Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells.
Mol Pharm
; 15(7): 2528-2538, 2018 07 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29874916
3.
A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.
J Med Chem
; 65(6): 4649-4666, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35255209
4.
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation.
Eur J Med Chem
; 216: 113265, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33652352
5.
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime.
Biomolecules
; 10(6)2020 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32512884
6.
New strategy for alerting central nervous system toxicity: Integration of blood-brain barrier toxicity and permeability in neurotoxicity assessment.
Toxicol In Vitro
; 23(3): 447-53, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19135142
7.
An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening.
Toxicol In Vitro
; 22(3): 799-811, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18280105
8.
Food-Derived Hemorphins Cross Intestinal and Blood-Brain Barriers In Vitro.
Front Endocrinol (Lausanne)
; 9: 159, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29692758
9.
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain.
J Med Chem
; 59(6): 2612-32, 2016 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26888301
10.
Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models.
Toxicol In Vitro
; 30(1 Pt A): 138-65, 2015 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26026931
11.
Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier.
Brain Res
; 1018(1): 1-9, 2004 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-15262198
12.
Mouse syngenic in vitro blood-brain barrier model: a new tool to examine inflammatory events in cerebral endothelium.
Lab Invest
; 85(6): 734-46, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15908914
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