Detalles de la búsqueda
1.
Performance and Sensitivity of [99mTc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver.
Mol Pharm
; 21(2): 932-943, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38225758
2.
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs.
Antimicrob Agents Chemother
; 67(3): e0149322, 2023 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36786609
3.
Dissimilar Effect of P-Glycoprotein and Breast Cancer Resistance Protein Inhibition on the Distribution of Erlotinib to the Retina and Brain in Humans and Mice.
Mol Pharm
; 20(11): 5877-5887, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37883694
4.
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice.
Int J Mol Sci
; 23(12)2022 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35742960
5.
Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharm Res
; 38(1): 127-140, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33559045
6.
In vivo characterization of [18F]AVT-011 as a radiotracer for PET imaging of multidrug resistance.
Eur J Nucl Med Mol Imaging
; 47(8): 2026-2035, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31729540
7.
Measurement of Hepatic ABCB1 and ABCG2 Transport Activity with [11C]Tariquidar and PET in Humans and Mice.
Mol Pharm
; 17(1): 316-326, 2020 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31790256
8.
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model.
Int J Mol Sci
; 21(21)2020 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33153231
9.
Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx ) with Knockout Capability.
Mol Pharmacol
; 96(2): 138-147, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31189668
10.
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
Mol Pharm
; 16(3): 1282-1293, 2019 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30694684
11.
Effect of Rifampicin on the Distribution of [11C]Erlotinib to the Liver, a Translational PET Study in Humans and in Mice.
Mol Pharm
; 15(10): 4589-4598, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30180590
12.
Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [11C]erlotinib and Positron Emission Tomography.
Drug Metab Dispos
; 45(10): 1093-1100, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28790147
13.
Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[11 C]verapamil in elderly vs. young subjects.
Br J Clin Pharmacol
; 83(9): 1991-1999, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28401570
14.
Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model.
Mol Pharmacol
; 89(5): 492-504, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26893303
15.
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-ß-d-allofuranosyl)-2-nitroimidazole (ß-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Bioorg Med Chem
; 24(21): 5326-5339, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27614920
16.
[18F]FE@SUPPY: a suitable PET tracer for the adenosine A3 receptor? An in vivo study in rodents.
Eur J Nucl Med Mol Imaging
; 42(5): 741-9, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25601336
17.
Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.
Mol Pharm
; 12(9): 3214-25, 2015 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26202880
18.
Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment.
Neurobiol Dis
; 72 Pt A: 54-60, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24746857
19.
Role of (drug) transporters in imaging in health and disease.
Drug Metab Dispos
; 42(12): 2007-15, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25249691
20.
[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier.
J Cereb Blood Flow Metab
; 44(1): 142-152, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37728771