Búsqueda | Biblioteca Virtual en Salud

1.

Absorption, metabolism and excretion of ¹⁴C-emvododstat following repeat daily oral dose administration in human volunteers using a combination of microtracer radioactivity and high radioactivity doses.

Ma, Jiyuan; Laskin, Oscar L; Roffel, Ad F; Vaes, Wouter H J; Tang, Bowen; Kolnaar, Jeroen; O'Keefe, Kylie; Golden, Lee; Kong, Ronald.

Drug Metab Dispos ; 2023 Oct 18.

Artículo en Inglés | MEDLINE | ID: mdl-37852795

2.

A clinical pharmacokinetic drug-drug interaction study between dextromethorphan and emvododstat, a potent anti-SARS-CoV-2 dihydroorotate dehydrogenase inhibitor.

Morton, Terri L; Laskin, Oscar L; Kaushik, Diksha; Lee, Lucy; Ma, Jiyuan; Bar, Cristian M; Kristensen, Allan; O'Keefe, Kylie; Golden, Lee; Klein, Matthew; Kong, Ronald.

Eur J Clin Pharmacol ; 79(8): 1073-1080, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37278823

3.

A pharmacokinetic drug-drug interaction study between rosuvastatin and emvododstat, a potent anti-SARS-CoV-2 (COVID-19) DHODH (dihydroorotate dehydrogenase) inhibitor.

Morton, Terri L; Laskin, Oscar L; Kaushik, Diksha; Lee, Lucy; Ma, Jiyuan; Kristensen, Allan; O'Keefe, Kylie; Golden, Lee; Klein, Matthew; Kong, Ronald.

Pharmacol Res Perspect ; 11(2): e01076, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36938928

4.

Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration.

Hoffmann, Matthew; Kumar, Gondi; Schafer, Peter; Cedzik, Dorota; Capone, Lori; Fong, Kei-Lai; Gu, Zheming; Heller, Dennis; Feng, Hao; Surapaneni, Sekhar; Laskin, Oscar; Wu, Anfan.

Xenobiotica ; 41(12): 1063-75, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21859393

5.

Pharmacokinetics and Safety of PTC596, a Novel Tubulin-Binding Agent, in Subjects With Advanced Solid Tumors.

Shapiro, Geoffrey I; O'Mara, Edward; Laskin, Oscar L; Gao, Lan; Baird, John D; Spiegel, Robert J; Kaushik, Diksha; Weetall, Marla; Colacino, Joseph; O'Keefe, Kylie; Branstrom, Arthur; Goodwin, Elizabeth; Infante, Jeffrey; Bedard, Philippe L; Kong, Ronald.

Clin Pharmacol Drug Dev ; 10(8): 940-949, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-33440067

6.

Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent.

Jernigan, Finith; Branstrom, Arthur; Baird, John D; Cao, Liangxian; Dali, Mandar; Furia, Bansri; Kim, Min Jung; O'Keefe, Kylie; Kong, Ronald; Laskin, Oscar L; Colacino, Joseph M; Pykett, Mark; Mollin, Anna; Sheedy, Josephine; Dumble, Melissa; Moon, Young-Choon; Sheridan, Richard; Mühlethaler, Tobias; Spiegel, Robert J; Prota, Andrea E; Steinmetz, Michel O; Weetall, Marla.

Mol Cancer Ther ; 20(10): 1846-1857, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34315764

7.

Ataluren Pharmacokinetics in Healthy Japanese and Caucasian Subjects.

Kong, Ronald; Laskin, Oscar L; Kaushik, Diksha; Jin, Fengbin; Ma, Jiyuan; McIntosh, Joseph; Souza, Marcio; Almstead, Neil.

Clin Pharmacol Drug Dev ; 8(2): 172-178, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30629861

8.

Pharmacokinetics of lenalidomide in subjects with various degrees of renal impairment and in subjects on hemodialysis.

Chen, Nianhang; Lau, Henry; Kong, Linghui; Kumar, Gondi; Zeldis, Jerome B; Knight, Robert; Laskin, Oscar L.

J Clin Pharmacol ; 47(12): 1466-75, 2007 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-17954615

9.

Clinical pharmacokinetics of thalidomide.

Teo, Steve K; Colburn, Wayne A; Tracewell, William G; Kook, Karin A; Stirling, David I; Jaworsky, Markian S; Scheffler, Michael A; Thomas, Steve D; Laskin, Oscar L.

Clin Pharmacokinet ; 43(5): 311-27, 2004.

Artículo en Inglés | MEDLINE | ID: mdl-15080764

10.

Distribution of lenalidomide into semen of healthy men after multiple oral doses.

Chen, Nianhang; Lau, Henry; Choudhury, Somesh; Wang, Xiaomin; Assaf, Mahmoud; Laskin, Oscar L.

J Clin Pharmacol ; 50(7): 767-74, 2010 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-20160158

11.

Lenalidomide: in vitro evaluation of the metabolism and assessment of cytochrome P450 inhibition and induction.

Kumar, Gondi; Lau, Henry; Laskin, Oscar.

Cancer Chemother Pharmacol ; 63(6): 1171-5, 2009 May.

Artículo en Inglés | MEDLINE | ID: mdl-19030860

12.

Evaluation of the developmental toxicity of lenalidomide in rabbits.

Christian, Mildred S; Laskin, Oscar L; Sharper, Valerie; Hoberman, Alan; Stirling, David I; Latriano, Louise.

Birth Defects Res B Dev Reprod Toxicol ; 80(3): 188-207, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17570132

13.

Clinical pharmacokinetics of thalidomide

Teo, Steve K; Colburn, Wayne A; Tracewell, William G; Kook, Karin A; Stirling, David I; Jaworsky, Markian S; Scheffer, Michael A; Thomas, Steve D; Laskin, Oscar L.

s.l; s.n; 2004. 17 p. ilus, tab, graf.

No convencional en Inglés | SES-SP, HANSEN, Hanseníase, SESSP-ILSLACERVO, SES-SP | ID: biblio-1242666

Biblioteca Virtual en Salud

Hipertensión

Su selección (0)

Formato de exportación:

Exportar: