Detalles de la búsqueda
1.
Synthetic Strategies toward Ortho-3-propanoate Substituted Aryl Phosphonates by Three-Component Coupling Reactions of Arynes, Phosphites, and Acrylates.
J Org Chem
; 89(11): 8035-8040, 2024 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38803278
2.
Identification of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one scaffolds as potent Lck inhibitors as anti-cancer agents.
Bioorg Med Chem Lett
; 102: 129645, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38316368
3.
Three-Component Coupling Reactions Involving Arynes, Phosphites, and Aldehydes toward 3-Mono-Substituted Benzoxaphosphole 1-Oxides.
J Org Chem
; 88(13): 8465-8479, 2023 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37224336
4.
Identification of highly selective type II kinase inhibitors with chiral peptidomimetic tails.
J Enzyme Inhib Med Chem
; 37(1): 1257-1277, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35484863
5.
Identification of novel pyrrolopyrimidine and pyrrolopyridine derivatives as potent ENPP1 inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 2434-2451, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36069240
6.
Efficient synthesis of mibefradil analogues: an insight into in vitro stability.
Org Biomol Chem
; 12(30): 5669-81, 2014 Aug 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24964394
7.
Synthesis and biological evaluation of aminobenzimidazole derivatives with a phenylcyclohexyl acetic acid group as anti-obesity and anti-diabetic agents.
Bioorg Med Chem Lett
; 23(16): 4713-8, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23810496
8.
Atroposelective desymmetrization of 2-arylresorcinols via Tsuji-Trost allylation.
Commun Chem
; 6(1): 42, 2023 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36841918
9.
Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy.
J Med Chem
; 66(22): 15141-15170, 2023 11 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37963811
10.
Synthetic Strategy for Aryl(alkynyl)phosphinates by a Three-Component Coupling Reaction Involving Arynes, Phosphites, and Alkynes.
Org Lett
; 24(45): 8295-8299, 2022 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36342701
11.
Acid-Catalyzed Hydrolysis and Intramolecular Cyclization of N-Cyano Sulfoximines for the Synthesis of Thiadiazine 1-Oxides.
ACS Omega
; 7(2): 2160-2169, 2022 Jan 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35071904
12.
Traceless solid-phase synthesis of 2,4,6-trisubstituted thiazolo[4,5-d]pyrimidine-5,7-dione derivatives.
J Comb Chem
; 11(3): 495-9, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19338271
13.
Enantioselective synthesis of (R)-(+)- and (S)-(-)-higenamine and their analogues with effects on platelet aggregation and experimental animal model of disseminated intravascular coagulation.
Bioorg Med Chem Lett
; 18(14): 4110-4, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18556200
14.
Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors.
Bioorg Med Chem Lett
; 18(24): 6525-9, 2008 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18996694
15.
Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors.
Eur J Med Chem
; 43(9): 1889-902, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18243422
16.
Enantioselective total synthesis of (-)-clavosolide B.
Org Lett
; 9(20): 3897-900, 2007 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-17824705
17.
Effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on platelet TXA2 synthesis and aggregation.
Thromb Res
; 120(1): 81-6, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17020781
18.
A limited series of synthetic tetrahydroisoquinoline alkaloids reduce inflammatory gene iNOS via inhibition of p-STAT-1 and suppress HMGB1 secretion in LPS-treated mice lung tissue.
Int Immunopharmacol
; 52: 297-304, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28982049
19.
Total synthesis, structural revision, and absolute configuration of (-)-clavosolide [corrected] A.
Org Lett
; 8(4): 661-4, 2006 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-16468736
20.
(S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coagulation.
Eur J Pharmacol
; 788: 200-209, 2016 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27343380