Detalles de la búsqueda
1.
Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure-activity relationships.
Bioorg Med Chem
; 91: 117403, 2023 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37418826
2.
Potent inhibitory activity of hydroxylated 2-benzylidene-3,4-dihydronaphthalen-1(2H)-ones on LPS-stimulated reactive oxygen species production in RAW 264.7 macrophages.
Bioorg Med Chem Lett
; 73: 128921, 2022 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35932905
3.
Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.
Bioorg Med Chem Lett
; 60: 128606, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35123005
4.
Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer's disease.
Bioorg Chem
; 108: 104681, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33571811
5.
4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships.
Bioorg Chem
; 116: 105349, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34536927
6.
Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
Bioorg Chem
; 111: 104884, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33872925
7.
Selective inhibitory effects of HYIpro-3-1 on CYP1A2 in human liver microsomes.
Biopharm Drug Dispos
; 42(1): 35-41, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33386627
8.
AK-I-190, a New Catalytic Inhibitor of Topoisomerase II with Anti-Proliferative and Pro-Apoptotic Activity on Androgen-Negative Prostate Cancer Cells.
Int J Mol Sci
; 22(20)2021 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681904
9.
Introduction of amino moiety enhances the inhibitory potency of 1-tetralone chalcone derivatives against LPS-stimulated reactive oxygen species production in RAW 264.7 macrophages.
Bioorg Chem
; 87: 495-505, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30927590
10.
Identification of DNA and glutathione adducts in male Sprague-Dawley rats exposed to 1-bromopropane.
J Toxicol Environ Health A
; 82(8): 502-513, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31140386
11.
Identification of sulfonyl-loxoprofen as novel phase 2 conjugate in rat.
Biopharm Drug Dispos
; 40(7): 234-241, 2019 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-31242324
12.
A novel anti-cancer agent, FPDHP, induces anoikis in various human cancer cells through activation of calpain, and downregulation of anoikis-related molecules.
J Cell Biochem
; 119(7): 5620-5631, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29388704
13.
Design, synthesis, and structure-activity relationships of new benzofuro[3,2-b]pyridin-7-ols as DNA topoisomerase II inhibitors.
Bioorg Med Chem Lett
; 28(4): 566-571, 2018 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29402741
14.
Synthesis and biological evaluation of pyridine-linked indanone derivatives: Potential agents for inflammatory bowel disease.
Bioorg Med Chem Lett
; 28(14): 2436-2441, 2018 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29910080
15.
Fabrication of hollow boron-doped diamond nanostructure via electrochemical corrosion of a tungsten oxide template.
Nanotechnology
; 29(32): 325602, 2018 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29786617
16.
A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships.
Bioorg Med Chem
; 26(18): 5212-5223, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30262132
17.
Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents.
Bioorg Med Chem
; 26(8): 1909-1919, 2018 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29510948
18.
Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines.
Bioorg Chem
; 79: 1-18, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29715635
19.
Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study.
Bioorg Med Chem Lett
; 27(5): 1205-1209, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28159411
20.
2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent.
Bioorg Med Chem Lett
; 27(15): 3279-3283, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28633898