Detalles de la búsqueda
1.
Modulation of peritumoral fibroblasts with a membrane-tethered tissue inhibitor of metalloproteinase (TIMP) for the elimination of cancer cells.
Invest New Drugs
; 40(1): 198-208, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34519970
2.
Targeting a Designer TIMP-1 to the Cell Surface for Effective MT1-MMP Inhibition: A Potential Role for the Prion Protein in Renal Carcinoma Therapy.
Molecules
; 24(2)2019 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30641935
3.
Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
Biochem J
; 443(1): 307-15, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22299597
4.
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
Biochem J
; 430(1): 79-86, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20533908
5.
The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function.
Biochemistry
; 49(29): 6184-92, 2010 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-20545310
6.
A Novel 3D Model for Visualization and Tracking of Fibroblast-Guided Directional Cancer Cell Migration.
Biology (Basel)
; 9(10)2020 Oct 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33049958
7.
The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition.
Biochem J
; 411(2): 433-9, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18215140
8.
Translocating a High-Affinity Designer TIMP-1 to the Cell Membrane for Total Renal Carcinoma Inhibition: Putting the Prion Protein to Good Use.
Mol Cell Biol
; 39(18)2019 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31208977
9.
Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition.
Oncotarget
; 8(14): 22685-22699, 2017 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186971
10.
ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4.
Biomed Rep
; 4(1): 73-78, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26870338
11.
Expanding the Activity of Tissue Inhibitors of Metalloproteinase (TIMP)-1 against Surface-Anchored Metalloproteinases by the Replacement of Its C-Terminal Domain: Implications for Anti-Cancer Effects.
PLoS One
; 10(8): e0136384, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26308720
12.
Mapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering.
Protein Sci
; 11(10): 2493-503, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12237470
13.
The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3.
FEBS Lett
; 520(1-3): 102-6, 2002 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-12044879
14.
Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity is in the detail.
Biochem Soc Symp
; (70): 65-80, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14587283
15.
The activity of a designer tissue inhibitor of metalloproteinases (TIMP)-1 against native membrane type 1 matrix metalloproteinase (MT1-MMP) in a cell-based environment.
Cancer Lett
; 290(1): 114-22, 2010 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19815335
16.
Identification of the extracellular matrix (ECM) binding motifs of tissue inhibitor of metalloproteinases (TIMP)-3 and effective transfer to TIMP-1.
J Biol Chem
; 282(9): 6887-98, 2007 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-17202148
17.
Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme.
J Biol Chem
; 280(16): 15967-75, 2005 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15713681
18.
Threonine 98, the pivotal residue of tissue inhibitor of metalloproteinases (TIMP)-1 in metalloproteinase recognition.
J Biol Chem
; 279(17): 17562-9, 2004 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-14734567
19.
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
J Biol Chem
; 279(43): 45121-9, 2004 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15308656
20.
Unveiling the surface epitopes that render tissue inhibitor of metalloproteinase-1 inactive against membrane type 1-matrix metalloproteinase.
J Biol Chem
; 278(41): 40224-30, 2003 Oct 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-12869573