Detalles de la búsqueda
1.
Identification and functional study of genetic polymorphisms in cyclic nucleotide phosphodiesterase 3A (PDE3A).
Ann Hum Genet
; 85(2): 80-91, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33249558
2.
Glucocorticoid receptor dimerization in the cytoplasm might be essential for nuclear localization.
Biochem Biophys Res Commun
; 553: 154-159, 2021 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33773137
3.
No impact of soluble epoxide hydrolase rs4149243, rs2234914 and rs751142 genetic variants on the development of type II diabetes and its hypertensive complication among Jordanian patients.
Int J Clin Pract
; 75(5): e14036, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33512081
4.
Identification and functional characterization of CYP4V2 genetic variants exhibiting decreased activity of lauric acid metabolism.
Ann Hum Genet
; 84(5): 400-411, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32396266
5.
Molecular Functionality of Cytochrome P450 4 (CYP4) Genetic Polymorphisms and Their Clinical Implications.
Int J Mol Sci
; 20(17)2019 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31480463
6.
Identification and characterization of amiodarone metabolites in rats using UPLC-ESI-QTOFMS-based untargeted metabolomics approach.
J Toxicol Environ Health A
; 81(12): 481-492, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29641932
7.
Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma.
Toxicol Appl Pharmacol
; 330: 100-106, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28729181
8.
Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis.
Arch Biochem Biophys
; 620: 43-51, 2017 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28347661
9.
Analysis of genetic polymorphism and biochemical characterization of a functionally decreased variant in prostacyclin synthase gene (CYP8A1) in humans.
Arch Biochem Biophys
; 569: 10-8, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25623425
10.
Determination of major UDP-glucuronosyltransferase enzymes and their genotypes responsible for 20-HETE glucuronidation.
J Lipid Res
; 55(11): 2334-42, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25249502
11.
Multiple cytochrome P450 isoforms are involved in the generation of a pharmacologically active thiol metabolite, whereas paraoxonase 1 and carboxylesterase 1 catalyze the formation of a thiol metabolite isomer from ticlopidine.
Drug Metab Dispos
; 42(1): 141-52, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24170778
12.
Development of a multiplex and cost-effective genotype test toward more personalized medicine for the antiplatelet drug clopidogrel.
Int J Mol Sci
; 15(5): 7699-710, 2014 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-24857912
13.
CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.
Antimicrob Agents Chemother
; 57(11): 5448-56, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23959307
14.
Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4.
Drug Metab Dispos
; 41(8): 1529-37, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23704698
15.
In vitro metabolism of obovatol and its effect on cytochrome P450 enzyme activities in human liver microsomes.
Biopharm Drug Dispos
; 34(4): 195-202, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23446989
16.
Exploring the Influence of VDR Genetic Variants TaqI, ApaI, and FokI on COVID-19 Severity and Long-COVID-19 Symptoms.
J Pers Med
; 13(12)2023 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38138892
17.
Clinical Significance of NAT2 Genetic Variations in Type II Diabetes Mellitus and Lipid Regulation.
Pharmgenomics Pers Med
; 16: 847-857, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37724295
18.
CYP2C19 Contributes to THP-1-Cell-Derived M2 Macrophage Polarization by Producing 11,12- and 14,15-Epoxyeicosatrienoic Acid, Agonists of the PPARγ Receptor.
Pharmaceuticals (Basel)
; 16(4)2023 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37111350
19.
Effects of testosterone and 17ß-oestradiol on expression of the G protein-coupled receptor P2Y12 in megakaryocytic DAMI cells.
Platelets
; 23(8): 579-85, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22746349
20.
Demand for Pharmacogenomics and Personalized Medicine in the United Arab Emirates.
J Pers Med
; 12(1)2022 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35055419