Detalles de la búsqueda
1.
Dihydroxyphenylglycol as a Biomarker of Norepinephrine Transporter Inhibition by Atomoxetine: Human Model to Assess Central and Peripheral Effects of Dosing.
J Clin Psychopharmacol
; 36(6): 675-683, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27755221
2.
A single-dose, 3-way crossover pharmacokinetic comparison between immediate-release oxycodone hydrochloride with aversion technology (IRO-A, Oxecta), IRO-a with Niacin, and Oxycodone Hydrochloride (Roxicodone) in healthy adults under fasting conditions.
Am J Ther
; 21(2): 99-105, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-22357166
3.
Aldafermin in patients with non-alcoholic steatohepatitis (ALPINE 2/3): a randomised, double-blind, placebo-controlled, phase 2b trial.
Lancet Gastroenterol Hepatol
; 7(7): 603-616, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35325622
4.
Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture.
Mol Endocrinol
; 23(2): 188-201, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19106195
5.
The effect of naltrexone on sleep parameters in healthy male volunteers.
J Clin Psychopharmacol
; 34(1): 167-8, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24346745
6.
Single-dose administration of MK-0657, an NR2B-selective NMDA antagonist, does not result in clinically meaningful improvement in motor function in patients with moderate Parkinson's disease.
J Clin Pharmacol
; 49(7): 856-64, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19491335
7.
LGD-5552, an antiinflammatory glucocorticoid receptor ligand with reduced side effects, in vivo.
Endocrinology
; 149(5): 2080-9, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18218700
8.
Biological characterization of a heterodimer-selective retinoid X receptor modulator: potential benefits for the treatment of type 2 diabetes.
Endocrinology
; 147(2): 1044-53, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16269450
9.
Mechanism of selective retinoid X receptor agonist-induced hypothyroidism in the rat.
Endocrinology
; 143(8): 2880-5, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12130551
10.
Activation of the retinoid X receptor suppresses appetite in the rat.
Endocrinology
; 145(2): 565-73, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-14605005
11.
Design, synthesis, and structure-activity relationship studies of novel 6,7-locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic acids.
J Med Chem
; 46(19): 4087-103, 2003 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12954061
12.
Similarity of insulin detemir pharmacokinetics, safety, and tolerability profiles in healthy caucasian and Japanese american subjects.
J Clin Pharmacol
; 44(3): 258-64, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-14973299
13.
A randomized, double-blind, placebo-controlled, multicenter, 28-day, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance.
J Clin Sleep Med
; 10(10): 1101-9, 2014 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25317091
14.
Dose proportionality and the effects of food on bioavailability of an immediate-release oxycodone hydrochloride tablet designed to discourage tampering and its relative bioavailability compared with a marketed oxycodone tablet under fed conditions: a single-dose, randomized, open-label, 5-way crossover study in healthy volunteers.
Clin Ther
; 34(7): 1601-12, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22717418
15.
RAR and RXR modulation in cancer and metabolic disease.
Nat Rev Drug Discov
; 6(10): 793-810, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17906642
16.
The effects of supratherapeutic doses of duloxetine on blood pressure and pulse rate.
J Cardiovasc Pharmacol
; 49(6): 384-93, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17577103
17.
QT effects of duloxetine at supratherapeutic doses: a placebo and positive controlled study.
J Cardiovasc Pharmacol
; 49(3): 146-53, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17414226
18.
Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.
J Biol Chem
; 279(19): 19721-31, 2004 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-14998989
19.
Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding protein in the regulation of adipogenesis.
J Biol Chem
; 279(23): 23908-15, 2004 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-15073165
20.
Design, synthesis and structure-activity relationship of novel RXR-selective modulators.
Bioorg Med Chem Lett
; 14(6): 1593-8, 2004 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15006411