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1.
Meropenem-ANT3310, a unique ß-lactam-ß-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii.
Antimicrob Agents Chemother
; 68(3): e0112023, 2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38289044
2.
Novel Specific Metallo-ß-Lactamase Inhibitor ANT2681 Restores Meropenem Activity to Clinically Effective Levels against NDM-Positive Enterobacterales.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33820763
3.
Discovery of a Novel Metallo-ß-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29530861
4.
Substituted α-mercaptoketones, new types of specific neprilysin inhibitors.
Bioorg Med Chem Lett
; 27(16): 3883-3890, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28676269
5.
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1ß in Cellular and Animal Infection Models.
ACS Infect Dis
; 9(2): 270-282, 2023 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36669138
6.
Synthesis and biological activities of topopyrones.
J Nat Prod
; 75(4): 577-85, 2012 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22462811
7.
Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors.
ACS Med Chem Lett
; 12(2): 217-227, 2021 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33603968
8.
Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors.
Bioorg Med Chem
; 18(10): 3481-93, 2010 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20456960
9.
ANT2681: SAR Studies Leading to the Identification of a Metallo-ß-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
ACS Infect Dis
; 6(9): 2419-2430, 2020 09 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32786279
10.
Discovery of ANT3310, a Novel Broad-Spectrum Serine ß-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.
J Med Chem
; 63(24): 15802-15820, 2020 12 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33306385
11.
SAR Studies Leading to the Identification of a Novel Series of Metallo-ß-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
ACS Infect Dis
; 5(1): 131-140, 2019 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30427656
12.
Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting.
Bioorg Med Chem Lett
; 18(23): 6240-3, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18929485
13.
Novel calcium sensing receptor ligands: a patent survey.
Expert Opin Ther Pat
; 21(5): 681-98, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21406038
14.
Synthesis and biological evaluation of cyclic nitrogen mustards based on carnitine framework.
Eur J Med Chem
; 45(9): 4140-8, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20615582
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