Detalles de la búsqueda
1.
KEYNOTE-434 part B: A phase 1 study evaluating the combination of epacadostat, pembrolizumab, and chemotherapy in Japanese patients with previously untreated advanced non-small-cell lung cancer.
Invest New Drugs
; 2024 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38530565
2.
The safety and tolerability of epacadostat alone and in combination with pembrolizumab in patients with advanced solid tumors: results from a first-in-Japanese phase I study (KEYNOTE-434).
Invest New Drugs
; 39(1): 152-162, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32564277
3.
Phase 1 study of epacadostat in combination with atezolizumab for patients with previously treated advanced nonsmall cell lung cancer.
Int J Cancer
; 147(7): 1963-1969, 2020 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32141617
4.
A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer.
Gynecol Oncol
; 146(3): 484-490, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28698009
5.
Radiographic progression by Prostate Cancer Working Group (PCWG)-2 criteria as an intermediate endpoint for drug development in metastatic castration-resistant prostate cancer.
BJU Int
; 114(6b): E25-E31, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24298897
6.
Clinical trials of R-(-)-gossypol (AT-101) in newly diagnosed and recurrent glioblastoma: NABTT 0602 and NABTT 0702.
PLoS One
; 19(1): e0291128, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38285688
7.
Ability of C-reactive protein to complement multiple prognostic classifiers in men with metastatic castration resistant prostate cancer receiving docetaxel-based chemotherapy.
BJU Int
; 110(11 Pt B): E461-8, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22520631
8.
Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study.
J Immunother Cancer
; 10(3)2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35288468
9.
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma.
Blood
; 111(11): 5350-8, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18292288
10.
An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer.
Clin Cancer Res
; 15(9): 3172-6, 2009 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19366825
11.
Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma.
J Immunother Cancer
; 7(1): 80, 2019 03 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30894212
12.
Epacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037).
J Clin Oncol
; 36(32): 3223-3230, 2018 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30265610
13.
Population Pharmacokinetic and Pharmacodynamic Modeling of Epacadostat in Patients With Advanced Solid Malignancies.
J Clin Pharmacol
; 57(6): 720-729, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27990653
14.
First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies.
Clin Cancer Res
; 23(13): 3269-3276, 2017 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28053021
15.
Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed.
J Clin Oncol
; 33(34): 4039-47, 2015 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26351344
16.
Acute and long-term toxicities associated with gemtuzumab ozogamicin (Mylotarg) therapy of acute myeloid leukemia.
Clin Lymphoma
; 2 Suppl 1: S29-34, 2002 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-11970768
17.
The treatment of acute myeloid leukemia in first relapse: a comprehensive review of the literature.
Leuk Lymphoma
; 43(9): 1715-27, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12685823
18.
Comparative efficacy and safety of gemtuzumab ozogamicin monotherapy and high-dose cytarabine combination therapy in patients with acute myeloid leukemia in first relapse.
Clin Adv Hematol Oncol
; 1(4): 220-5, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16224410
19.
Efficacy of docetaxel-based chemotherapy following ketoconazole in metastatic castration-resistant prostate cancer: implications for prior therapy in clinical trials.
Urol Oncol
; 31(8): 1457-63, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22552048
20.
Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts.
J Hematol Oncol
; 6(1): 81, 2013 Oct 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-24283202